Impact of blood pressure lowering on ventricular repolarization heterogeneity in patients with newly diagnosed hypertension
Yazarlar (2)
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ataç ÇELİK
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | BLOOD PRESSURE MONITORING |
| Dergi ISSN | 1359-5237 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q4 |
| Makale Dili | Türkçe |
| Basım Tarihi | 12-2021 |
| Cilt No | 26 |
| Sayı | 6 |
| Sayfalar | 407 / 412 |
| DOI Numarası | 10.1097/MBP.0000000000000551 |
| Makale Linki | http://dx.doi.org/10.1097/mbp.0000000000000551 |
| Özet |
| Objective Frontal plane QRS-T (fQRS-T) angle is a marker of ventricular repolarization heterogeneity and increased fQRS-T angle is associated with arrhythmias, adverse events and mortality. However, little is known about the importance and usefulness of fQRS-T angle in hypertensive patients. The present study aimed to investigate the association between blood pressure (BP) levels and fQRS-T angle. The main goal was to demonstrate whether BP lowering has a favorable effect on fQRS-T angle in hypertensive patients. Methods This study included 392 newly diagnosed hypertensive patients who underwent antihypertensive therapy. Responders and nonresponders to antihypertensive therapy were compared regarding baseline and post-treatment fQRS-T angle. fQRS-T angle was calculated as the absolute difference between QRS and T wave axes that were obtained from electrocardiography. Response to treatment was defined as achieving BP levels <140/90 mmHg. Results At the 1-month follow-up visit, responders had significantly lower fQRS-T angle compared to nonresponders despite the similar baseline fQRS-T angle (baseline: 57°±18.2° vs.56.6°±16.3°; P=0.819, at 1month: 36.9°±13.7 vs.53.5°±15.6°; P<0.001). Moreover, after 3months of antihypertensive treatment, both responders at 1month and 3months had significantly lower fQRS-T angle compared to nonresponders (34.8°±13.3° vs. 35.4°±12.9° vs. 52.3°±13.9°; P<0.001). Furthermore, a significant moderate positive correlation was observed between systolic BP and fQRS-T angle (r:0.797; P<0.001), and between diastolic BP and fQRS-T angle (r:0.761; P<0.001). Conclusion In the present study, a significant decrease in fQRS-T angle was observed following BP lowering throughout the study period. Therefore, fQRS-T angle may be useful in the monitoring of antihypertensive treatment. Blood Press Monit 26: 407-412. |
| Anahtar Kelimeler |
| Antihypertensive treatment | Blood pressure lowering | Electrocardiography | Frontal plane QRS-T angle | Hypertension |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 3 |
| SCOPUS | 2 |
| Google Scholar | 4 |