Cardiotrophin 1 Plasma Levels are Increased in Patients with Diastolic Heart Failure
Yazarlar (10)
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Şemsettin Şahin
Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Fatih Koç Akdeniz Üniversitesi, Türkiye
Dr. Öğr. Üyesi Metin KARAYAKALI Gaziosmanpaşa Üniversitesi, Türkiye
Mehmet Şahin Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İsmail Benli
Gaziosmanpaşa Üniversitesi, Türkiye
Hasan Kadı
Balıkesir Üniversitesi, Türkiye
Turgay Burucu
Gaziosmanpaşa Üniversitesi, Türkiye
Köksal Ceyhan
Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ünal Erkorkmaz Sakarya Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Medical Science Monitor (Q4)
Dergi ISSN 1234-1010
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2012
Cilt / Sayı / Sayfa 18 / 1 / – DOI 10.12659/MSM.882197
Makale Linki https://medscimonit.com/download/index/idArt/882197
UAK Araştırma Alanları
Kardiyoloji
Özet
Summary Background Cardiotrophin-1 (CT-1) is a member of the interleukin (IL-6) family of cytokines and is increased in various cardiovascular diseases, including chronic heart failure. The aim of the study was to determine if plasma CT-1 is associated with diastolic heart failure (DHF) and to investigate the relationship between CT-1 and echocardiographic parameters. Material/Methods Fifty-seven consecutive patients (mean age 57±8 years, 24 males) diagnosed with DHF in our clinic and 33 controls (mean age 55±7 years, 12 males) were included in the study. All study participants underwent echocardiographic evaluation and blood samples were obtained. Results CT-1 and NT-proBNP values were significantly higher in DHF subjects than in controls (11.30 [8.09–16.51] vs. 17.5 [8.95–28.74] fmol/mL, P=0.017 and 64 [27.5–95] vs. 82 [55.5–241] pg/mL, P=0.009, respectively). The mitral peak velocity of early …
Anahtar Kelimeler
Cardiotrophin-1 | Diastolic heart failure | N-terminal pro-B-type natriuretic peptide | Tissue doppler echocardiography
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 18
Scopus 20
Google Scholar 40
Cardiotrophin 1 Plasma Levels are Increased in Patients with Diastolic Heart Failure

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