Sodium bicarbonate versus isotonic saline for the prevention of contrast induced nephropathy in patients with diabetes mellitus undergoing coronary angiography and or intervention a multicenter prospective randomized study
 
Yazarlar (11)
Dr. Öğr. Üyesi Fatih Koç Akdeniz Üniversitesi, Türkiye
Kurtuluş Özdemir Necmettin Erbakan Üniversitesi, Türkiye
Fatih Altunkaş
Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Orhan Doğdu
Fırat Üniversitesi, Türkiye
Dr. Öğr. Üyesi Metin KARAYAKALI Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Enes Elvin Gül Necmettin Erbakan Üniversitesi, Türkiye
Prof. Dr. Ünal Erkorkmaz Sakarya Üniversitesi, Türkiye
Hasan Kadı
Balıkesir Üniversitesi, Türkiye
Mahmut Akpek
Adnan Menderes Üniversitesi, Türkiye
Mehmet Güngör Kaya Erciyes Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of Investigative Medicine (Q4)
Dergi ISSN 1708-8267 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SSCI
Makale Dili İngilizce Basım Tarihi 01-2013
Cilt / Sayı / Sayfa 61 / 5 / 872–877 DOI 10.2310/JIM.0b013e31828e9cab
Makale Linki https://journals.sagepub.com/doi/10.2310/JIM.0b013e31828e9cab
UAK Araştırma Alanları
Kardiyoloji
Özet
IntroductionContrast-induced nephropathy (CIN) is a leading cause of acute renal failure and affects mortality and morbidity. Although the incidence of CIN is quite low in the general population, CIN incidence is significantly increased in patients with diabetes mellitus (DM).ObjectivesWe compared the efficacy of prophylactic use consisting of a saline infusion or a sodium bicarbonate infusion for the prevention of CIN in patients with DM.Materials and MethodsA total of 195 DM patients who had unselected renal function were randomized into 2 groups: 101 patients were assigned to saline infusion, and 94 patients were assigned to bicarbonate infusion. The primary end point was the maximum increase in the serum creatinine (SCr) level, whereas the secondary end point was the development of CIN after the procedure.ResultsThe maximum increase in SCr levels was significantly lower in the saline group than in the …
Anahtar Kelimeler
Contrast-induced nephropathy | Diabetes mellitus | Isotonic saline | Sodium bicarbonate