Bioassay-guided isolation and identification of antioxidant flavonoids from Cyclotrichium origanifolium (Labill.) manden and scheng
Yazarlar (4)
Abdussamat Güzel Harran Üniversitesi, Türkiye
Doç. Dr. Hüseyin Akşit Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Mahfuz Elmastaş Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Pharmacognosy Magazine (Q3) | ||
| Dergi ISSN | 0973-1296 Dergi Bilgileri (2017) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2017 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-01-2017 |
| Cilt / Sayı / Sayfa | 13 / 50 / 316–320 | DOI | 10.4103/0973-1296.204556 |
| Makale Linki | http://www.phcog.com/text.asp?2017/13/50/316/204556 | ||
| UAK Araştırma Alanları |
Biyokimya
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| Özet |
| Background Medicinal and aromatic plants play a significant role in drug discovery and development process. Flavonoids, revealing a wide spectrum of biological activities, extensively found in plants are important secondary metabolites. Materials and Methods Aerial parts of Cyclotrichium origanifolium were collected, dried, and boiled in water then extracted with hexane, ethyl acetate, and n-butanol. Total phenolic content, DPPH• scavenging activity, reducing power (FRAP) activity, and ABTS•+ scavenging activity assays were applied for all extracts. The ethyl acetate extract revealing the most antioxidant activity as well as including the highest phenolic contents was subjected to chromatographic techniques (column chromatography, sephadex LH-20, semipreparative HPLC) to isolate the active compounds. The structure of isolated compounds were elucidated by spectroscopic methods (1D NMR, 2D NMR, and … |
| Anahtar Kelimeler |
| antioxidant activity | Cyclotrichium origanifolium | flavonoids | isolation | spectroscopy |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Yöksis | 24 |
| Yöksis | 6 |
| Web of Science | 41 |
| Scopus | 44 |
| Google Scholar | 76 |