Phytochemical Investigation of Hypericum heterophyllum Flowers: LC-ESI-MS/MS Analysis, Total Phenolic and Flavonoid Contents, Antioxidant Activity
Yazarlar (4)
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Cennet Yaman Yozgat Bozok University, Türkiye
Prof. Dr. İbrahim Demirtaş Iğdır Üniversitesi, Türkiye
Mehmet Hakkı Alma Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Natural Products Journal
Dergi ISSN 2210-3155 Dergi Bilgileri (2023)
Dergi Tarandığı Indeksler E-SCI
Makale Dili Türkçe Basım Tarihi 01-2023
Kabul Tarihi 31-10-2022 Yayınlanma Tarihi 01-11-2023
Cilt / Sayı / Sayfa 13 / 7 / 37–45 DOI 10.2174/2210315513666230112165545
Makale Linki http://dx.doi.org/10.2174/2210315513666230112165545
UAK Araştırma Alanları
Organik Kimya
Özet
Background Hypericum heterophyllum has been used as a traditional medicine and includes significant bioactive compounds. Objective To quantitatively determine the phenolic and flavonoid contents of Hypericum heterophyllum flowers and evaluate the antioxidant activity. Also, to present the activity-compound relationship. Methods Flowers of H. heterophyllum Vent., endemic species for Turkey were collected from Yozgat-Turkey. H. heterophyllum flowers were extracted with methanol, ethanol, acetone, and chloroform individually. LC-ESI-MS/MS analysis for phytochemicals was carried out for each extract. Total phenolic and flavonoid content were carried out for each extract. The antioxidant activity was performed using DPPH•, ABTS•+, hydroxyl radical, and superoxide radical scavenging assays. Results Chlorogenic acid was found as a major compound in all extracts. Among the extracts, methanol extract …
Anahtar Kelimeler
acetone | antioxidant activity | flavonoid | Hypericum heterophyllum | natural products | quantitative analysis