Synthesis and characterization of silver nanoparticles using curcumin: cytotoxic, apoptotic, and necrotic effects on various cell lines
Yazarlar (3)
Tünay Karan Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Öğr. Gör. Büşra Moran Bozer Hitit University, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Zeitschrift Fur Naturforschung Section C Journal of Biosciences (Q3)
Dergi ISSN 0939-5075 Dergi Bilgileri (2022)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 07-2022
Kabul Tarihi – Yayınlanma Tarihi 23-02-2022
Cilt / Sayı / Sayfa 77 / 7 / 343–350 DOI 10.1515/znc-2021-0298
Makale Linki https://www.degruyter.com/document/doi/10.1515/znc-2021-0298/pdf
UAK Araştırma Alanları
Organik Kimya Spektroskopi Nanoteknoloji
Özet
Nanostructures have distinctive chemical and physical features owing to their surface area and nanoscale size. In this study, silver nanoparticles were synthesized using curcumin, a medicinally valuable natural product. The structure of curcumin-mediated silver nanoparticles (c-AgNPs) was identified by extensive spectroscopic techniques. The maximum absorption was observed at 430 nm in UV–Vis spectrum. The crystal structure of c-AgNPs was identified by XRD. The morphology of the structure was determined by SEM image. The particle size was found as 51.13 nm. The functional groups of curcumin and c-AgNPs were established by FTIR spectroscopy. Cytotoxic activity of c-AgNPs was carried out using A549, DLD-1, and L929 with MTT assay. c-AgNPs revealed excellent activity on DLD-1 cell lines and A549 cell lines at 1.0 mg/mL concentration with the lethal effect of 80%. However, nanoparticles did not …
Anahtar Kelimeler
apoptosis | curcumin | cytotoxicity | necrosis | silver nanoparticles