A theoretical study of oleuropein derivatives as drugs
Yazarlar (2)
Faik Gökalp Kirikkale Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Turkish Computational and Theoretical Chemistry | ||
| Dergi ISSN | 2587-1722 Dergi Bilgileri (2022) | ||
| Dergi Tarandığı Indeksler | Scopus, Chemical Abstract Service | ||
| Makale Dili | Türkçe | Basım Tarihi | 03-2022 |
| Kabul Tarihi | 21-03-2022 | Yayınlanma Tarihi | 15-12-2022 |
| Cilt / Sayı / Sayfa | 6 / 2 / 18–21 | DOI | 10.33435/TCANDTC.977727 |
| Makale Linki | http://dx.doi.org/10.33435/tcandtc.1055649 | ||
| UAK Araştırma Alanları |
Organik Kimya
Spektroskopi
Nanoteknoloji
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| Özet |
| Oleuropein is a natural product revealing a large variety of biological activity. The natural products are functionalized to increase the activity in the pharmaceutical industry. Theoretical calculations were carried out for oleuropein derivatives to display the target compound exhibiting the most biological effects. Hence, synthetic chemists are able to get inspired to synthesize the most active oleuropein derivatives. The chemical properties of oleuropein derivatives have been investigated theoretically. Gaussian method was used for quantum calculations of these compounds. The properties of compounds were presented and the utilization of these compounds in pharmaceutical industries was investigated. The quantum calculations revealed that 2H-oleuropein (3) and 4-aminobutyl-2-oleuropein (2) were unstable and were prone to react to the radical compounds. |
| Anahtar Kelimeler |
| 2H-oleuropein | 4-aminobutyl-2-oleuropein | Gaussian | Oleuropein |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |