Chemical composition, acetylcholine esterase and Anti-bacterial activities of essential oils of Elaeosilenum thapsioides (Desf.) Maire from Algeria
Yazarlar (9)
Zakaria Barbeche Université Oum El Bouaghi, Cezayir
Hocine Laouer Université Ferhat Abbas Sétif 1, Cezayir
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Mohamed Hajji Ecole Nationale D'ıngénieurs De Sfax, Tunus
Guido Flamini Università Di Pisa, İtalya
Ylenia Pieracci Università Di Pisa, İtalya
Latifa Khattabi Centre De Recherche En Biotechnologie, Cezayir
Chawki Bensouici Centre De Recherche En Biotechnologie, Cezayir
Salah Akkal Université Constantine 1, Cezayir
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Current Topics in Medicinal Chemistry (Q2)
Dergi ISSN 1568-0266 Dergi Bilgileri (2021)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2021
Kabul Tarihi 27-07-2021 Yayınlanma Tarihi 22-12-2021
Cilt / Sayı / Sayfa 21 / 29 / 2610–2619 DOI 10.2174/1568026621666210813110847
Makale Linki http://dx.doi.org/10.2174/1568026621666210813110847
UAK Araştırma Alanları
Organik Kimya
Özet
Background Traditionally, the Algerian medicinal plant Elaeosilenum thapsioides (Desf.) Maire has been used for many diseases. The present research work aims to explore the chemical and biological characterization of its essential oil. Methods The essential oils were obtained by hydrodistillation of different Elaeosilenum thapsioides (Apiaceae) aerial parts samples collected from two different regions (Mahouane and Megres) from Setif, Eastern Algeria. The chemical characterization of the obtained essential oils is reported here for the first time. Besides, they were evaluated for their in vitro Acetylcholinesterase (AChE) inhibitory activity involved in Alzheimer’s disease using Ellman’s spectrophotometric method. Results Additionally, their in vitro antimicrobial activity was assessed by the disc diffusion method. Both activities were performed at various oil concentrations. The GC/MS analysis of the essential oils …
Anahtar Kelimeler
Algeria | Anti-bacterial activity | Anti-cholinesterase activity | Elaeosilenum thapsioides | Essential oils | GC-MS