Diterpenes from the berries of Juniperus excelsa
Yazarlar (7)
Bezm-İ Âlem Vakıf Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Phytochemistry |
| Dergi ISSN | 0031-9422 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI |
| Dergi Grubu | Q4 |
| Makale Dili | İngilizce |
| Basım Tarihi | 04-1999 |
| Cilt No | 50 |
| Sayı | 7 |
| Sayfalar | 1195 / 1199 |
| DOI Numarası | 10.1016/S0031-9422(98)00675-X |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S003194229800675X |
| Özet |
| From the hexane extract of berries of Juniperus excelsa, one new and four known diterpenes were isolated besides a known sesquiterpene. The structures of the known diterpenes were identified as isopimaric, isocommunic, (-)ent-trans communic and sandracopimaric acids, along with the sesquiterpene 4a-hydroxycedrol and the new compound which was elucidated as 3 alpha-acetoxylabda-8(17),13(16),14-trien-19-oic acid (juniperexcelsic acid). Cytotoxic activity of the hexane extract was investigated against a panel of cell line and found highly active against LNCaP, KB-V (+VLB) and KB-V (-VLB) cell lines. Furthermore, the hexane and methanol extracts, and the new compound were found to be moderately active against Mycobacterium tuberculosis. |
| Anahtar Kelimeler |
| Juniperus excelsa | Cupressaceae | berries | diterpenes | juniperexcelsic acid | sesquiterpene | cytotoxic | antituberculosis and antibacterial activity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 99 |