Diterpenes from the berries of Juniperus excelsa
Yazarlar (7)
Gülaçti Topçu Tubıtak Marmara Research Center, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Osman Çakmak Faculty of Engineering And Architecture, Türkiye
Candan Bozok Johansson Marmara Üniversitesi, Türkiye
Cennet Çelik Marmara Üniversitesi, Türkiye
Hee Byung Chai University of Illinois At Chicago, Amerika Birleşik Devletleri
John M. Pezzuto University of Illinois At Chicago, Amerika Birleşik Devletleri
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Phytochemistry (Q2) | ||
| Dergi ISSN | 0031-9422 Dergi Bilgileri (1999) | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-1999 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-04-1999 |
| Cilt / Sayı / Sayfa | 50 / 7 / 1195–1199 | DOI | 10.1016/S0031-9422(98)00675-X |
| Makale Linki | http://linkinghub.elsevier.com/retrieve/pii/S003194229800675X | ||
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| From the hexane extract of berries of Juniperus excelsa, one new and four known diterpenes were isolated besides a known sesquiterpene. The structures of the known diterpenes were identified as isopimaric, isocommunic, (−)ent-trans communic and sandracopimaric acids, along with the sesquiterpene 4a-hydroxycedrol and the new compound which was elucidated as 3a-acetoxylabda-8 (17),13 (16),14-trien-19-oic acid (juniperexcelsic acid). Cytotoxic activity of the hexane extract was investigated against a panel of cell line and found highyl active against LNCaP, KB-V (+VLB) and KB-V (−VLB) cell lines. Furthermore, the hexane and methanol extracts, and the new compound were found to be moderately active against Mycobacterium tuberculosis. |
| Anahtar Kelimeler |
| Antituberculosis and antibacterial activity | Berries | Cupressaceae | Cytotoxic | Diterpenes | Juniperexcelsic acid | Juniperus excelsa | Sesquiterpene |
Science Direct
Diterpenes from the berries of Juniperus excelsa
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Yöksis | 47 |
| Web of Science | 105 |
| Scopus | 117 |
| Google Scholar | 203 |