Short and Selective Synthesis of 3 5 dibromoinden 1 one
Yazarlar (3)
Derya Çelik
Ahmet Tutar Sakarya Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(Diğer hakemli uluslarası dergilerde yayınlanan tam makale)
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| Dergi Adı | Journal of New Results in Science | ||
| Dergi ISSN | 1304-7981 | ||
| Dergi Tarandığı Indeksler | google scholar | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2012 |
| Cilt / Sayı / Sayfa | 1 / 1 / 1–4 | DOI | – |
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| Brominations of hydrocarbons are important processes in synthetic chemistry. Bromoindanes and bromoindenones are key intermediate for medicinally valuable compounds. Short and efficient synthesis of 3,5-dibromoinden-1-one is presented. 5-bromoindane-1-one 1 was treated with ethylene glycol to mask the ketone functional group to yield the cyclic ketal 2. Bromination of bromoindanecyclic ketal 2 with bromine in photochemical reaction apparatus while being irradiated with a projector lamp afforded the product which was treated with silica gel directly to remove the protective group afforded the corresponding 3,5-dibromoinden-1-one 3 |
| Anahtar Kelimeler |
