Acute effects of moxonidine on cardiac autonomic modulation
Yazarlar (5)
Dayimi Kaya
Izmir Dr. Suat Seren Chest Disease And Thoracic Surgery Training Hospital, Türkiye
Izmir Dr. Suat Seren Chest Disease And Thoracic Surgery Training Hospital, Türkiye
Prof. Dr. Irfan Barutcu Avicenna Hospital, Türkiye
Ali Metin Esen
Kartal Education And Research Hospital, Türkiye
Kartal Education And Research Hospital, Türkiye
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ersel Onrat Afyon Kocatepe Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | PACE Pacing and Clinical Electrophysiology (Q4) | ||
| Dergi ISSN | 0147-8389 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2010 |
| Cilt / Sayı / Sayfa | 33 / 8 / 929–933 | DOI | 10.1111/j.1540-8159.2010.02727.x |
| Makale Linki | https://onlinelibrary.wiley.com/doi/10.1111/j.1540-8159.2010.02727.x | ||
| UAK Araştırma Alanları |
Kardiyoloji
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| Özet |
| Background: Moxonidine, an imidazoline I1 receptor agonist, is a centrally acting antihypertensive agent having sympatholytic effect. However, there are only limited data regarding the effects of this drug on autonomic cardiac functions. Methods and results: In this study we investigated the acute effects of moxonidine on cardiac autonomic modulation by heart rate variability (HRV) analysis. The effects of oral 0.4‐mg moxonidine were studied on 11 healthy male volunteers in a randomized, double‐blind, placebo controlled, and crossover study. After 15 minutes rest, time and frequency domain parameters of HRV were calculated from 5‐minute continue electrocardiography recordings in supine position, during controlled respiration (15 breath/min) and during handgrip exercise before and 1 hour after taking placebo or moxonidine. Baseline parameters before taking placebo and moxonidine were … |
| Anahtar Kelimeler |
| electrocardiogram | noninvasive risk assessment tests |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 2 |
| Google Scholar | 7 |