Isolation and identification of chemical constituents from Origanum majorana and investigation of antiproliferative and antioxidant activities
Yazarlar (7)
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ozkan Sen Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Huseyin Aksit Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ibrahim Demirtas Çankiri Karatekin Üniversitesi, Türkiye
Ayse Sahin Yaglioglu Çankiri Karatekin Üniversitesi, Türkiye
Mahfuz Elmastas Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Isa Telci Süleyman Demirel Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Journal of the Science of Food and Agriculture (Q1)
Dergi ISSN 0022-5142 Dergi Bilgileri (2016)
Dergi Tarandığı Indeksler SCI
Makale Dili İngilizce Basım Tarihi 02-2016
Kabul Tarihi 23-02-2015 Yayınlanma Tarihi 08-04-2015
Cilt / Sayı / Sayfa 96 / 3 / 822–836 DOI 10.1002/jsfa.7155
Makale Linki http://doi.wiley.com/10.1002/jsfa.7155
UAK Araştırma Alanları
Organik Kimya
Özet
BACKGROUND Origanum majorana L., belonging to the Lamiaceae family, has great potential and has been used as a folk medicine against asthma, indigestion, headache and rheumatism; in addition, the essential oils of this plant have been used widely in the food industry. Plant materials have been harvested from the Medicinal and Aromatic Plant Field of Gaziosmanpasa University. Air‐dried plant materials were boiled in water, filtered, and the solvent part subsequently extracted with hexane and ethyl acetate. The chromatographic method was applied to the ethyl acetate extract to isolate bioactive secondary metabolites, the structures of which were elucidated by spectroscopic techniques: basically one‐dimensional and two‐dimensional nuclear magnetic resonance and quadrupole time‐of‐flight liquid chromatography. Antiproliferative and antioxidant activities of isolated secondary metabolites were …
Anahtar Kelimeler
Antioxidant activity | Antiproliferative activities | Chemical constituents | Origanum majorana | Structure elucidation