Quantification of flavonoids isolated from Mentha spicata in selected clones of Turkish mint landraces     
Yazarlar (8)
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İsa Telci
Isparta Uygulamalı Bilimler Üniversitesi, Türkiye
Mahfuz Elmastaş
Sağlık Bilimleri Üniversitesi, Türkiye
Hüseyin Akşit
Erzincan Binali Yıldırım Üniversitesi, Türkiye
Fatih Gül
Çankırı Karatekin Üniversitesi, Türkiye
Ali Rıza Tüfekçi
Çankırı Karatekin Üniversitesi, Türkiye
İbrahim Demirtaş
Çankırı Karatekin Üniversitesi, Türkiye
Ömer Kayır
Hitit Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Turkish Journal of Chemistry
Dergi ISSN 1300-0527 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 12-2018
Cilt No 42
Sayı 6
Sayfalar 1695 / 1705
DOI Numarası 10.3906/kim-1712-3
Makale Linki http://online.journals.tubitak.gov.tr/openDoiPdf.htm?mKodu=kim-1712-3
Özet
Mint has been used extensively in traditional medicines, spices, and herbal teas throughout the world.Isolation of flavonoids from Mentha spicata and quantification of these compounds in selected clones of Turkish mintslandraces were achieved. M. spicata was dried in shade and then boiled in water. After filtration, the aqueous extractwas partitioned with ethyl acetate. The solvent was removed under reduced pressure to yield the extract, subjected tosilica gel column chromatography to isolate 5-demethyl sinensetin (1), hesperidin (2), didymin (3), and linarin (4), thestructures of which were elucidated by 1D NMR, 2D NMR, and LC-TOF/MS. The isolated compounds were employedas standard flavonoids to determine the quantitative variations in cultivated Turkish mint landraces belonging to Mentha× piperita L., M. spicata L., and M. × villosonervata Opiz by HPLC. The quantities of hesperidin (2), didymin (3), andlinarin (4) in M. spicata were found as 11.83, 3.85, and 42.21 mg/g dried plant weight (DW), respectively, while that of5-demethyl sinensetin (1) in M. villosonervata was 2.9 mg/g DW. Consisting of pharmaceutically valuable compounds,M. spicata and cultivated Turkish mint landraces could be a source of 5-demethyl sinensetin (1), hesperidin (2), didymin(3), and linarin (4).
Anahtar Kelimeler
Mentha species | flavonoid | quantification | isolation