Quantification of flavonoids isolated from Mentha spicata in selected clones of Turkish mint landraces
Yazarlar (8)
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. İsa Telci Isparta Uygulamalı Bilimler Üniversitesi, Türkiye
Prof. Dr. Mahfuz Elmastaş Sağlık Bilimleri Üniversitesi, Türkiye
Doç. Dr. Hüseyin Akşit Erzincan Binali Yıldırım Üniversitesi, Türkiye
Dr. Öğr. Üyesi Fatih Gül Çankırı Karatekin Üniversitesi, Türkiye
Ali Rıza Tüfekçi Çankırı Karatekin Üniversitesi, Türkiye
Prof. Dr. İbrahim Demirtaş Çankırı Karatekin Üniversitesi, Türkiye
Öğr. Gör. Ömer Kayır Hitit Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Turkish Journal of Chemistry (Q3)
Dergi ISSN 1300-0527 Dergi Bilgileri (2018)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2018
Kabul Tarihi – Yayınlanma Tarihi 06-12-2018
Cilt / Sayı / Sayfa 42 / 6 / 1695–1705 DOI 10.3906/kim-1712-3
Makale Linki http://online.journals.tubitak.gov.tr/openDoiPdf.htm?mKodu=kim-1712-3
UAK Araştırma Alanları
Organik Kimya
Özet
Mint has been used extensively in traditional medicines, spices, and herbal teas throughout the world. Isolation of flavonoids from Mentha spicata and quantification of these compounds in selected clones of Turkish mints landraces were achieved. M. spicata was dried in shade and then boiled in water. After filtration, the aqueous extract was partitioned with ethyl acetate. The solvent was removed under reduced pressure to yield the extract, subjected to silica gel column chromatography to isolate 5-demethyl sinensetin (1), hesperidin (2), didymin (3), and linarin (4), the structures of which were elucidated by 1D NMR, 2D NMR, and LC-TOF/MS. The isolated compounds were employed as standard flavonoids to determine the quantitative variations in cultivated Turkish mint landraces belonging to Mentha x piperita L., M. spicata L., and M. x villosonervata Opiz by HPLC. The quantities of hesperidin (2), didymin (3), and linarin (4) in M. spicata were found as 11.83, 3.85, and 42.21 mg/g dried plant weight (DW), respectively, while that of 5-demethyl sinensetin (1) in M. villosonervata was 2.9 mg/g DW. Consisting of pharmaceutically valuable compounds, M. spicata and cultivated Turkish mint landraces could be a source of 5-demethyl sinensetin (1), hesperidin (2), didymin (3), and linarin (4).
Anahtar Kelimeler
Flavonoid | Isolation | Mentha species | Quantification
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Yöksis 5
Web of Science 24
Scopus 31
Google Scholar 49
TR Dizin 4
Quantification of flavonoids isolated from Mentha spicata in selected clones of Turkish mint landraces