Isolation and identification of a new neo clerodane diterpenoid fromTeucrium chamaedrys L
Yazarlar (7)
Mahfuz Elmastas Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Besir Isnac Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Huseyin Aksit Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ozkan Sen Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Nusret GENÇ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ibrahim Demirtas Çankiri Karatekin Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Natural Product Research (Q2)
Dergi ISSN 1478-6419 Dergi Bilgileri (2016)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 02-2016
Kabul Tarihi – Yayınlanma Tarihi 11-08-2015
Cilt / Sayı / Sayfa 30 / 3 / 299–304 DOI 10.1080/14786419.2015.1057583
Makale Linki http://www.tandfonline.com/doi/full/10.1080/14786419.2015.1057583
UAK Araştırma Alanları
Organik Kimya
Özet
Teucrium chamaedrys L. is an aromatic and medicinal plant used as traditional medicine. Aerial parts of the plant material were dried and extracted with hexane–dichloromethane (extract 1), ethyl acetate–dichloromethane (extract 2) and methanol–dichloromethane (extract 3) in a ratio of 1:1 at rt successively. The solvents were evaporated to give crude extracts. Extract 1 was suspended in water at 60°C then partitioned successively with hexane and ethyl acetate to give hexane and ethyl acetate portions. After the column chromatography (silica gel) of ethyl acetate extract, one new and four known compounds were isolated. The new compound was named as 1(12S,18R)-15,16-epoxy-2β,6β-dihydroxy-neo-cleroda-13(16),14-dien-20,l2-olide-l8,l9-hemiacetal (teuchamaedryn D) (4). The known compounds were teucrin A (1), dihydroteugin (2), teucroxide (3), syspirensin A (5). The chromatographic methods were also …
Anahtar Kelimeler
neo-clerodane diterpenoid | teuchamaedryn D | Teucrium chamaedrys L