Isolation and identification of a new neo clerodane diterpenoid fromTeucrium chamaedrys L
Yazarlar (7)
Mahfuz Elmastaş Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Isnaç Beşir
Hüseyin Akşit Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Özkan Şen
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Nusret GENÇ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İbrahim Demirtaş Çankırı Karatekin Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | NATURAL PRODUCT RESEARCH (Q4) | ||
| Dergi ISSN | 1478-6419 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2016 |
| Cilt / Sayı / Sayfa | 30 / 3 / 299–304 | DOI | 10.1080/14786419.2015.1057583 |
| Makale Linki | http://www.tandfonline.com/doi/full/10.1080/14786419.2015.1057583 | ||
| Özet |
| Teucrium chamaedrys L. is an aromatic and medicinal plant used as traditional medicine. Aerial parts of the plant material were dried and extracted with hexane-dichloromethane (extract 1), ethyl acetate-dichloromethane (extract 2) and methanol-dichloromethane (extract 3) in a ratio of 1:1 at rt successively. The solvents were evaporated to give crude extracts. Extract 1 was suspended in water at 60°C then partitioned successively with hexane and ethyl acetate to give hexane and ethyl acetate portions. After the column chromatography (silica gel) of ethyl acetate extract, one new and four known compounds were isolated. The new compound was named as 1(12S,18R)-15,16-epoxy-2β,6β-dihydroxy-neo-cleroda-13(16),14-dien-20,l2-olide-l8,l9-hemiacetal (teuchamaedryn D) (4). The known compounds were teucrin A (1), dihydroteugin (2), teucroxide (3), syspirensin A (5). The chromatographic methods were also applied for extract 3 to isolate verbascoside (6) and teucrioside (7). The structure of isolated compounds was elucidated by spectroscopic methods including LC-TOF/MS, 1D NMR and 2D NMR. |
| Anahtar Kelimeler |
| Teucrium chamaedrys L | teuchamaedryn D | neo-clerodane diterpenoid |
| Atıf Sayıları | |
| Web of Science | 36 |