1-Methyl-4-ethynylpridinum triflate: Reaction with Thiophenol Giving Rise to Chromophoric (E)-1-methyl-4-[2-(phenylsulfanyl)-1-ethenyl] pyridinium triflate. An Example of ...
Yazarlar (2)
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Jean-Francois Biellmann
| Makale Türü | Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN | ||
| Dergi ISSN | 0253-5106 Dergi Bilgileri (2012) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 10-2012 |
| Cilt / Sayı / Sayfa | 34 / 5 / 1224–1228 | DOI | – |
| Makale Linki | https://scholar.google.com/scholar?cluster=7195858176107152659&hl=en&oi=scholarr | ||
| UAK Araştırma Alanları |
Organik Kimya
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| Özet |
| 1-Methyl-4-ethynylpridinum triflate 6 was prepared by treatment of 4-ethynylpyridine 5 with methyl triflate in dichloromethane. Thiophenol added to the triple bond to give regioselectively (E)-1-methyl-4-[2-(phenylsulfanyl)-1-ethenyl] pyridinium triflate 7. The addition of glutathione to 1-methyl-4-ethynylpridinum triflate 6 with in TES buffer at pH 7 was a second order reaction (k= 4200 M-1 s-1 at 25 0C). The addition products showed an intense long wavelength absorption band (lmax= 360 nm, e= 27500 M-1 cm-1). The reaction rate and the spectroscopic properties show the usefulness of 4-ethynyl-1-methylpridinium triflate 6 as reagent for the determination of thiol. |
| Anahtar Kelimeler |
| Chromophores | pyridinium salts | glutathione | coupling reactions | thiol determination |
