Is diastolic dysfunction associated with atrial electrocardiographic parameters in Behcet s Disease      
Yazarlar (12)
Fatih Koc
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Sema Koc
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Jale Yuksek
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Mehmet Akif Vatankulu
Etlik Ihtisas Education And Research Hospital, Türkiye
Kerem Ozbek
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Enes Elvin Gul
Selçuk Üniversitesi, Türkiye
Prof. Dr. Ataç ÇELİK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ahmet Inanir
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Hasan Kadi
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Koksal Ceyhan
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Metin Karayakali
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ahmet Ozturk
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı ACTA CARDIOLOGICA
Dergi ISSN 0001-5385 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 01-2011
Cilt No 66
Sayı 5
Sayfalar 607 / 612
DOI Numarası 10.2143/AC.66.5.2131086
Özet
Background The impact of Behçet's disease (BD) on the vascular bed is highly important, as this condition may lead to heart failure from asymptomatic systolic and diastolic dysfunction. Our aim was to evaluate diastolic functions using new echocardiographic parameters and the correlation of these parameters with atrial electrocardiographic (ECG) indices in patients with BD. Methods 31 patients with BD and 31 healthy control subjects were enrolled to this study. Left ventricular (LV) diastolic functions were examined with conventional and tissue Doppler echocardiography. P-wave dispersion (PD) was calculated by measuring minimum and maximum P-wave duration values on the 12-lead surface ECG. The relationship between PD and echocardiographic parameters of diastolic dysfunction were investigated. Results The mitral infl ow E/A ratio and diastolic myocardial velocity ratio (Em/Am) were lower in the BD group (P < 0.001 and P < 0.001, respectively). The E/Em ratio and left atrial volume index (LAVi) were higher in the BD group (P < 0.001 and P = 0.014, respectively) compared to healthy control subjects. P max and PD were signifi cantly higher in the BD group (P < 0.001 and P < 0.001). PD correlated positively with the duration of BD. Also, PD correlated positively with LAVi and E/Em ratio, but negatively with E/A and Em/Am ratios. Conclusion In this study, we demonstrated that LV diastolic functions are impaired in BD patients. Furthermore, P-wave abnormalities were demonstrated in BD patients and there was a signifi cant correlation between PD and diastolic dysfunction.
Anahtar Kelimeler
Behçet's disease | Diastolic dysfunction | Left atrial volume index | P-wave dispersion