Effects of non - surgical periodontal therapy on inflammatory markers of psoriasis: A randomized controlled trial
Yazarlar (3)
Doç. Dr. Fatma Uçan Yarkaç Necmettin Erbakan Üniversitesi, Türkiye
Prof. Dr. Atiye AKBAYRAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Özge Göktürk
Bolu Abant İzzet Baysal Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı JOURNAL OF CLINICAL PERIODONTOLOGY (Q1)
Dergi ISSN 0303-6979 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 01-2020
Cilt / Sayı / Sayfa 47 / 2 / 193–201 DOI 10.1111/jcpe.13205
Makale Linki https://onlinelibrary.wiley.com/doi/abs/10.1111/jcpe.13205
UAK Araştırma Alanları
Deri ve Zührevi Hastalıkları
Özet
AbstractAimThe purpose of this randomized controlled clinical study was to evaluate the effect of non‐surgical mechanical periodontal therapy on the inflammatory status and severity of psoriasis in subjects with psoriasis.Material and methodsThe study population consisted of 92 periodontitis patients with psoriasis vulgaris suffering from an untreated periodontal disease. Two randomized groups were formed from these patients: immediate periodontal therapy (test group,n = 46) and delayed periodontal therapy (control group,n = 46). Periodontal clinical measures, on salivary interleukin 2, interleukin 6 and secretory immunoglobulin A levels and the Psoriasis Area and Severity Index (PASI) scores were evaluated at baseline and on the 8th week in control and test groups.ResultsEight weeks after completion of non‐surgical periodontal therapy (test group) or initial examination (control group), a significant decrease was observed in interleukin 2, interleukin 6 level and in PASI score, whereas a significant increase was observed in secretory immunoglobulin A levels in the test group (p < .05).ConclusionWithin the limits of this study, the results suggest that effective periodontal therapy improves the psoriasis condition in patients afflicted by both diseases.
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