Synthesis, structural characterization, electrochemical, photoluminescence, antiproliferative and antioxidant properties of Co(II), Cu(II) and Zn(II) complexes bearing the azo-azomethine ligands      
Yazarlar (8)
Esin Ispir
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Mesut Ikiz
University Of Health Sciences, Türkiye
Ayşe Inan
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Ali Burak Sünbül
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Doç. Dr. Seçil ERDEN TAYHAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Sema BİLGİN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Muhammet Köse
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Mahfuz Elmastaş
University Of Health Sciences, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı Journal of Molecular Structure
Dergi ISSN 0022-2860 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q3
Makale Dili İngilizce
Basım Tarihi 04-2019
Cilt No 1182
Sayı 1
Sayfalar 63 / 71
DOI Numarası 10.1016/j.molstruc.2019.01.029
Makale Linki http://dx.doi.org/10.1016/j.molstruc.2019.01.029
Özet
Co(II), Cu(II) and Zn(II) complexes derived from azo-azomethine compounds were synthesized and characterized by a combination of magnetic susceptibility, elemental analyses, FTIR and UV–Visible spectroscopies. The characterized complexes were found to be mononuclear and the chelation of the ligands to the metal ions occurs through phenolic oxygen and nitrogen atoms of the azomethine group of the ligands. Solid state structure of 5 was determined by single crystal X-ray diffraction studies. The electrochemical and photoluminescence properties of the synthesized compounds were also studied. In order to evaluate the ability of the compounds to inhibit cell proliferation, we treated MCF7 (breast cancer), PC3 (prostate cancer) and H2126 (lung cancer) cells with different concentrations of Co(II), Cu(II) and Zn(II) complexes bearing the azo-azomethine ligands. When nine Co(II), Cu(II) and Zn(II) complexes were assessed within themselves, our results highlighted that three compounds (8, 9 and 10) had the best inhibitory activity on all cell lines.
Anahtar Kelimeler
Azo-azomethine | Metal complexes | Anticancer activity | Antioxidant properties | Electrochemical