Glial Cell Line-Derived Neurotrophic Factor, S-100 Protein and Synaptophysin Expression in Biliary Atresia Gallbladder Tissue
Yazarlar (14)
Semra Gürünlüoğlu
Canan Ceran Özcan
Türkiye
Türkiye
Prof. Dr. Kubilay Gürünlüoğlu Türkiye
Alper Koçbıyık
Türkiye
Türkiye
Prof. Dr. Mehmet Gül İnönü Üniversitesi, Türkiye
Prof. Dr. Turan Yıldız Türkiye
Prof. Dr. Harika Gözde Gözükara Bağ İnönü Üniversitesi, Türkiye
Dr. Öğr. Üyesi Semir GÜL İnönü Üniversitesi, Türkiye
Aytaç Taşçi
Ercan Bayrakçı
Türkiye
Türkiye
Dr. Öğr. Üyesi Necmettin Akpınar Türkiye
Ecem Serbest Çin
Türkiye
Türkiye
Öğr. Gör. Hasan Ateş Türkiye
Prof. Dr. Mehmet Demircan Türkiye
| Makale Türü | Özgün Makale (Diğer hakemli uluslarası dergilerde yayınlanan tam makale) | ||
| Dergi Adı | Pediatric Gastroenterology, Hepatology & Nutrition | ||
| Dergi ISSN | 2234-8646 Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2021 |
| Cilt / Sayı / Sayfa | 24 / 2 / 173– | DOI | 10.5223/pghn.2021.24.2.173 |
| Makale Linki | http://dx.doi.org/10.5223/pghn.2021.24.2.173 | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| Purpose Biliary atresia (BA) is a disease that manifests as jaundice after birth and leads to progressive destruction of the ductal system in the liver. The aim of this study was to investigate histopathological changes and immunohistochemically examine the expression of glial cell line-derived neurotrophic factor (GDNF), synaptophysin, and S-100 protein in the gallbladder of BA patients. Methods The study included a BA group of 29 patients and a control group of 41 children with cholecystectomy. Gallbladder tissue removed during surgery was obtained and examined immunohistochemically and histopathologically. Tissue samples of both groups were immunohistochemically assessed in terms of GDNF, S-100 protein, and synaptophysin expression. Expression was classified as present or absent. Inflammatory activity assessment with hematoxylin and eosin staining and fibrosis assessment with Masson's trichrome … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 1 |