Protective effects of crocin on acrylamide-induced testis damage
Yazarlar (7)
Prof. Dr. Mehmet Gül İnönü Üniversitesi, Türkiye
Elif Kayhan Kuştepe
Prof. Dr. Mehmet Erman Erdemli İnönü Üniversitesi, Türkiye
Eyüp Altınöz Türkiye
Dr. Öğr. Üyesi Semir GÜL İnönü Üniversitesi, Türkiye
Nurcan Göktürk
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ANDROLOGIA (Q3) | ||
| Dergi ISSN | 0303-4569 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 10-2021 |
| Cilt / Sayı / Sayfa | 53 / 9 / – | DOI | 10.1111/and.14176 |
| Makale Linki | Accepted for publicaiton, not published yet | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| Exposure to acrylamide (Ac) through food is almost inevitable and this kind of toxicity may cause lifelong harm. In present study, we researched effects of Crocin (Cr) on testis histopathology in Ac‐induced testis of rats. Adult male rats were grouped as: group 1, 1 ml saline only; group 2, 50 mg/kg Cr only; group 3, 25 mg/kg Ac only and group 4, 25 mg/kg Ac + 50 mg/kg Cr. All administrations were given as 1 ml/day by gavage for 21 days. It was found that Ac adversely influenced the levels of FSH, testosterone and LH in the blood serum; malondialdehyde (MDA), total antioxidant status (TOS), oxidative stress index (OSI)/ glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), total antioxidant status (TAS) oxidant/antioxidant parameters in testis tissue (p < .01) and the histopathological parameters like Johnson's score, seminiferous tubule diameter, seminiferous epithelial height and H‐score for caspase‐3 … |
| Anahtar Kelimeler |
| acrylamide | crocin | histopathology | oxidative stress | testis |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 15 |
| Google Scholar | 25 |