Is Decorin a Promising New Agent for Facial Nerve Regeneration? An Experimental Study
Yazarlar (8)
Zehra Çınar
Türkiye
Türkiye
Ufuk Emre
Türkiye
Türkiye
Prof. Dr. Mehmet Gül İnönü Üniversitesi, Türkiye
Arş. Gör. Özgür Yiğit Türkiye
Elshan Mammadov
Prof. Dr. Enes Yiğit Türkiye
Dr. Öğr. Üyesi Semir GÜL Türkiye
Hilal Rumeyza Cırık
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Audiology and Neurotology (Q4) | ||
| Dergi ISSN | 1420-3030 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 01-2021 |
| Cilt / Sayı / Sayfa | 26 / 3 / 195–205 | DOI | 10.1159/000512003 |
| Makale Linki | http://dx.doi.org/10.1159/000512003 | ||
| UAK Araştırma Alanları |
Histoloji ve Embriyoloji
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| Özet |
| Objective: The aim of this study was to investigate the effects of systemic administration of decorin (DC) on facial nerve (FN) regeneration. Methods: A total of 32 female albino Wistar rats were divided into 4 groups: control (C) group: no bilateral FN neurorrhaphy (B-FNN), no DC application, sham-operated group: B-FNN without DC application, DC group: DC application without B-FNN, and B-FNN + DC group: B-FNN and DC application. Nerve conduction studies were performed before and after skin incisions at 1st, 3rd, 5th, and 7th weeks in all groups. The amplitude and latency of compound muscle action potentials were recorded. FN samples were obtained and were investigated under light microscopy and immunohistochemical staining. The nerve and axon diameter, number of axons, H score, Schwann cell proliferation, and myelin and axonal degeneration were recorded quantitatively … |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 2 |