Structural changes in periodontium of rats exposed to a low concentration of hydrogen sulfide for 50 days    
Yazarlar (5)
Defne Yalçın Yener
Turgay Hocaoglu
Melike Koraltan
Mehmet Gül
İnönü Üniversitesi, Türkiye
Dr. Öğr. Üyesi Semir GÜL İnönü Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı European Journal of Inflammation
Dergi ISSN 1721-727X Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 08-2016
Cilt No 14
Sayı 2
Sayfalar 93 / 99
DOI Numarası 10.1177/1721727X16659289
Makale Linki http://journals.sagepub.com/doi/10.1177/1721727X16659289
Özet
The aim of the present study was to investigate the effect of H2S inhalation at a low concentration (at human equivalent dose of pathologic halitosis) on rat periodontium over a long term (50 days). The threshold level of pathologic halitosis perceived by humans at 250 ppb of H2S was converted to rat equivalent concentration (4.15 ppm). Rats in the experimental (H2S) group (n = 8) were exposed to H2S continuously but not the control rats (n = 8). After 50 days, periodontal tissue samples were taken from the mandibular first molar region and examined histopathologically to determine inflammatory cell infiltration (ICI), osteoblastic activities, number of osteoclasts, and resorption lacunae.Sulcular epithelium layer destruction was observed in the H2S group. Frequency of ICI was significantly higher in the H2S group compared to the control group (P <0.05). The number of osteoclasts were found significantly higher in …
Anahtar Kelimeler
hydrogen sulfide | halitosis | Howship's lacunae | periodontal tissue