Prevalence of insulin resistance and identifying HOMA1-IR and HOMA2-IR indexes in the Middle Black Sea region of Turkey      
Yazarlar (10)
Ayşe Kevser Demir
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Şafak ŞAHİN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Süheyla UZUN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İlknur Bütün
Türkiye
Doç. Dr. Rıza ÇITIL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Yalçın Önder
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Türker TAŞLIYURT Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Osman DEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Köksal DEVECİ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Faruk Kutlutürk
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı African Health Sciences
Dergi ISSN 1680-6905 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 04-2020
Cilt No 20
Sayı 1
Sayfalar 277 / 286
DOI Numarası 10.4314/ahs.v20i1.33
Makale Linki https://www.ajol.info/index.php/ahs/issue/view/18844
Özet
Insulin resistance (IR) is one of the most important etiological risk factors in the development of diabetes. However, there is no clear data regarding the prevalence of IR in the country. This study evaluates the prevalence of IR and identifies the optimal threshold values for the HOMA indexes in Turkey. This cross-sectional, population-based survey includes 2013 participants aged 20-84 years. The values of the anthropometric measurements and laboratory analysis were recorded. The 90 percentile in the non-obese and non-diabetic population was accepted as cut-off values for IR. The optimal threshold values for IR were 2.46 in HOMA1-IR and 1.40 in HOMA2-IR. Using the HOMA2-IR method, the overall prevalence of IR was 33.2%. The IR prevalence was higher in women (35.6%) compared to men (30.1%) [p=0.008]. There was a higher IR prevalence in men living in urban areas (p=0.001), not in women. The multivariate logistic regression analysis showed that gender, serum glucose level, serum levels of triglycerides and high-density lipoprotein cholesterol, bodymass index and income status were associated with insulin resistance. The cut-off values of HOMA1-IR and HOMA2-IR were determined in this study and we believe that these findings will be helpful to clinicians in the fight against health problems such as diabetes.
Anahtar Kelimeler
Insulin resistance | HOMA | diabetes mellitus