Assesment of Autonomic Function in Metabolic Syndrome using Combination Heart Rate Variability and Heart Rate Turbulence   
Yazarlar (7)
Gülay Aydın
Savaş Sarıkaya
Bozok Üniversitesi, Türkiye
Okan Onur Turgut
Cumhuriyet Üniversitesi, Türkiye
Doç. Dr. Şafak ŞAHİN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Nuray Yılmaz Çakmak
Mehmet Birhan Yılmaz
Cumhuriyet Üniversitesi, Türkiye
İzzet Tandoğan
Makale Türü Özgün Makale
Makale Alt Türü Diğer hakemli uluslarası dergilerde yayınlanan tam makale
Dergi Adı Acta Medica Anatolia
Dergi Tarandığı Indeksler Türk Tıp Dizini
Makale Dili İngilizce
Basım Tarihi 01-2013
Özet
Objectives: Metabolic syndrome (MetS) is described as a group of various abnormal metabolic risk factors such as obesity, dyslipidemia, increased blood pressure, increased plasma glucose levels, prothrombotic condition and proinflammatory state. These parameters are related to decreased parasympathetic and increased sympathetic activity. We aimed to evaluate autonomic function using a combination with heart rate variability (HRV) and heart rate turbulence (HRT) in metabolic syndrome to compare non-metabolic syndrome (non-MetS).Methods: We selected consecutive 50 patients with MetS and 50 patients with healthy non-MetS individuals. All patients underwent 24 hours holter monitoring to evaluate HRT and HRV parameters. Results: Age of patients was not different in two groups. Mean age of MetS patients was 57, 50±12, 13 and 54, 6±10, 25 in non-MetS individuals. Sex of patients was non different in MetS compared to non-MetS (37 female and 13 male vs. 22 female, 28 male p< 0, 05 respectively). SDNN and RMSSD was lower in MetS compared to those without MetS (131, 96±49, 12 vs 179, 59±85, 83 p= 0, 03 and 78, 64±35, 22 vs 112, 73±81, 24 p= 0, 08 respectively). SDANN, pNN50, Mean RR, mean heart rate, count of ventricular premature complex (VPC) were not different between two groups. Turbulence Slope (TS) was not different in two groups. Turbulence Onset (TO) was higher in MetS compared to non-MetS (2, 01±15, 29 and-6, 21±13, 5 p= 0,005). Conclusions: We showed that autonomic function in MetS was impaired using a combination with HRT and HRV. These patients should be followed closely for adverse …
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