Prevalence of insulin resistance and identifying HOMA1-IR and HOMA2-IR indexes in the Middle Black Sea region of Turkey
Yazarlar (10)
Prof. Dr. Ayşe Kevser Demir Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Şafak ŞAHİN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Süheyla UZUN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
İlknur Bütün
Türkiye
Türkiye
Doç. Dr. Rıza ÇITIL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Yalçın Önder
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Türker TAŞLIYURT Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Osman DEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Köksal DEVECİ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Faruk Kutlutürk
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | African Health Sciences (Q2) | ||
| Dergi ISSN | 1680-6905 Dergi Bilgileri (2020) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 04-2020 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 20-04-2020 |
| Cilt / Sayı / Sayfa | 20 / 1 / 277–286 | DOI | 10.4314/ahs.v20i1.33 |
| Makale Linki | https://www.ajol.info/index.php/ahs/issue/view/18844 | ||
| UAK Araştırma Alanları |
İç Hastalıkları
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| Özet |
| Background: Insulin resistance (IR) is one of the most important etiological risk factors in the development of diabetes. How- ever, there is no clear data regarding the prevalence of IR in the country. Objective: This study evaluates the prevalence of IR and identifies the optimal threshold values for the HOMA indexes in Turkey. Methods: This cross-sectional, population-based survey includes 2013 participants aged 20–84 years. The values of the anthro- pometric measurements and laboratory analysis were recorded. The 90th percentile in the non-obese and non-diabetic population was accepted as cut-off values for IR. Results: The optimal threshold values for IR were 2.46 in HOMA1-IR and 1.40 in HOMA2-IR. Using the HOMA2-IR method, the overall prevalence of IR was 33.2%. The IR prevalence was higher in women (35.6%) compared to men (30.1%) [p=0.008]. There was a higher IR prevalence in men living in urban areas (p=0.001), not in women. The multivariate logistic regression analysis showed that gender, serum glucose level, serum levels of triglycerides and high-density lipoprotein cholesterol, body- mass index and income status were associated with insulin resistance. Conclusion: The cut-off values of HOMA1-IR and HOMA2-IR were determined in this study and we believe that these find- ings will be helpful to clinicians in the fight against health problems such as diabetes. Keywords: Insulin resistance; HOMA; diabetes mellitus. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Yöksis | 14 |