Anticholinergic and antioxidant activities of avocado (Folium perseae) leaves-phytochemical content by LC-MS/MS analysis
       
Yazarlar (9)
Leyla Polat Kose T.C. Beykent Üniversitesi, Türkiye
Dr. Öğr. Üyesi Zeynebe BİNGÖL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Ruya Kaya
Atatürk Üniversitesi, Türkiye
Ahmet C. Goren
Bezmiâlem Vakıf Üniversitesi, Türkiye
Hulya Akincioglu Aǧrı İbrahim Çeçen Üniversitesi, Türkiye
Lokman Durmaz Erzincan Binali Yıldırım Üniversitesi, Türkiye
Ekrem Koksal Erzincan Binali Yıldırım Üniversitesi, Türkiye
Saleh H. Alwasel
College Of Sciences, Suudi Arabistan
İlhami Gülçin Atatürk Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı International Journal of Food Properties (Q3)
Dergi ISSN 1094-2912 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 06-2020
Cilt / Sayı / Sayfa 23 / 1 / 878–893 DOI 10.1080/10942912.2020.1761829
Makale Linki https://doi.org/10.1080/10942912.2020.1761829
Özet
In the first stage of the manuscript, we aimed to examine antioxidant capacity and anticholinergic properties of avocado (Folium perseae) leaves. Avocado leaf was extracted by water (WEFP) and ethyl alcohol (EEFP) and antioxidant activity was determined using by several antioxidant assays including DPPH· and ABTS•+ radical scavenging assays, Cu2+-Cu+ reducing, Fe3+-Fe2+ reducing, and FRAP reducing activities. Avocado leaf extracts demonstrated antioxidant activity and anticholinergic activities, while α-tocopherol, BHT, trolox, and BHA were used as positive antioxidant controls. In the second part of this study, the inhibition effects of WEFP and EEFP were valuated against acetylcholinesterase and butyrylcholinesterase enzymes, which catalyze the breakdown of choline esters (i.e. neurotransmitters). This study obviously showed that avocado leaf extracts had effective antioxidant, antiradical, and anticholinergic influences.
Anahtar Kelimeler
acetylcholinesterase | antioxidant activity | Avocado | butyrylcholinesterase | Folium perseae | radical scavenging