Antidiabetic, anticholinergic and antioxidant activities of aerial parts of shaggy bindweed (Convulvulus betonicifolia Miller subsp.) – profiling of phenolic compounds by LC-HRMS
        
Yazarlar (8)
Dr. Öğr. Üyesi Zeynebe BİNGÖL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Hatice Kızıltaş Van Yüzüncü Yıl Üniversitesi, Türkiye
Ahmet C. Gören
Bezmiâlem Vakıf Üniversitesi, Türkiye
Leyla Polat Kose T.C. Beykent Üniversitesi, Türkiye
Meryem Topal Gümüşhane Üniversitesi, Türkiye
Lokman Durmaz Erzincan Binali Yıldırım Üniversitesi, Türkiye
Saleh H. Alwasel
College Of Sciences, Suudi Arabistan
İlhami Gulcin Atatürk Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Heliyon (Q4)
Dergi ISSN 2405-8440 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 01-2021
Cilt / Sayı / Sayfa 7 / 5 / – DOI 10.1016/j.heliyon.2021.e06986
Makale Linki http://dx.doi.org/10.1016/j.heliyon.2021.e06986
Özet
In order to evaluate the antioxidant activity of evaporated ethanolic extract (EESB) and lyophilized water extract (WESB) of Shaggy bindweed (Convulvulus betonicifolia Mill. Subs), some putative antioxidant methods such as DPPH· scavenging activity, ABTS•+ scavenging effect, ferric ions (Fe3+) reduction method, cupric ions (Cu2+) reducing capacity, and ferrous ions (Fe2+) binding activities were separately performed. Also, ascorbic acid, α-tocopherol and BHT were used as the standard compounds. Additionally, some phenolic compounds that responsible for antioxidant abilities of EESB and WESB were screened by liquid chromatography-high resolution mass spectrometry (LC-HRMS). At the same concentration, EESB and WESB demonstrated effective antioxidant abilities when compared to standards. In addition, EESB demonstrated IC50 values of 1.946 μg/mL against acetylcholinesterase (AChE), 0.815 μg/mL against α-glycosidase and 0.675 μg/mL against α-amylase enzymes.
Anahtar Kelimeler
Antioxidant activity | Convulvulus betonicifolia | LC-HRMS | Polyphenol content | Shaggy bindweed