Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
Yazarlar (6)
Sağlık Bilimleri Üniversitesi, Türkiye
Doç. Dr. Aykut ÖZGÜR
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Kırşehir Ahi Evran Üniversitesi, Türkiye
Kırşehir Ahi Evran Üniversitesi, Türkiye
Università Degli Studi Di Genova, İtalya
Università Degli Studi Di Genova, İtalya
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) |
| Makale Alt Türü | SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale |
| Dergi Adı | Biomedicine and Pharmacotherapy |
| Dergi ISSN | 0753-3322 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 10-2016 |
| Cilt No | 83 |
| Sayı | 1 |
| Sayfalar | 1182 / 1190 |
| DOI Numarası | 10.1016/j.biopha.2016.08.043 |
| Makale Linki | https://www.sciencedirect.com/science/article/abs/pii/S0753332216306916?via%3Dihub |
| Özet |
| Lung cancer is one of the most common mortal cancer types both for men and women. Several different biomarkers have been analyzed to reveal lung cancer prognosis pathways for developing efficient therapeutics and diagnostic agents. microRNAs (miRNAs) and pseudogenes are critical biomarkers in lung cancer and alteration of their expression levels has been identified in each step of lung cancer tumorigenesis. miRNAs and pseudogenes are crucial gene regulators in normal cells as well as in lung cancer cells, and they have both oncogenic and tumor-suppressive roles in lung cancer tumorigenesis. In this study, we have determined the relationship between lung cancer related oncogenes and miRNAs along with pseudogenes in lung cancer, and the results indicate their potential as biological markers for diagnostic and therapeutic purposes. |
| Anahtar Kelimeler |
| Biomarker | Lung cancer | miRNA | miRNA therapeutics | Pseudogene |
Science Direct
Regulation of oncogenic genes by MicroRNAs and pseudogenes in human lung cancer
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| SCOPUS | 29 |
| Google Scholar | 29 |