A Novel Deep Learning Architecture Optimization for Multiclass Classification of Alzheimer’s Disease Level      
Yazarlar (2)
Doç. Dr. Mahir KAYA Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Yasemin ÇETİN KAYA Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı IEEE Access
Dergi ISSN 2169-3536 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q2
Makale Dili İngilizce
Basım Tarihi 03-2024
Cilt No 12
Sayı 1
Sayfalar 46562 / 46581
DOI Numarası 10.1109/ACCESS.2024.3382947
Makale Linki http://dx.doi.org/10.1109/access.2024.3382947
Özet
Alzheimer's disease is a neurodegenerative disorder prevalent in older adults, and early diagnosis is crucial for effective treatment. A deep learning model can automatically classify Alzheimer's disease from magnetic resonance imaging to aid clinicians in diagnosis. Convolutional Neural Networks (CNNs) are commonly used for disease detection in medical images, but their performance is limited due to inadequate labeled data, high inter-class similarity, and overfitting problems. Key hyperparameters influencing CNN performance include the number of convolution layers and filters assigned to each convolution layer. About other hyperparameters, numerous combinations exist. Since CNN models take a long time to train, it is quite costly to try all combinations to find the optimal model. Existing studies have optimized only a few hyperparameters, such as learning rate, batch size, and optimizer in custom and transfer learning models. In this study, we propose an algorithm based on particle swarm optimization to fine-tune the hyperparameters, including the number of convolution layers, filters, and other hyperparameters, in CNN architectures designed to classify Alzheimer's disease severity. Using the proposed lightweight model, Alzheimer's disease was accurately classified with an accuracy of 99.53% and an F1-score of 99.63% on a public dataset. Our model surpasses the performance of previous studies, offering the potential to alleviate the burden on doctors and expedite their decision-making processes. The developed framework can be accessed via the link: 'https://ai.gop.edu.tr/alzheimer'.
Anahtar Kelimeler
Alzheimer's disease | Convolutional neural networks | Training | Magnetic resonance imaging | Feature extraction | Computer architecture | Deep learning | Optimization methods | Hyperparameter optimization | convolutional neural network | Alzheimer | optimization | hyperparameter