Hypovitaminosis D in Children with Familial Mediterranean Fever
Yazarlar (7)
Prof. Dr. Resul Yılmaz Selçuk Üniversitesi, Türkiye
Doç. Dr. Erhan KARAASLAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Samet Özer Türkiye
Ergün Sönmezgöz
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Nafia Özlem Kazancı Türkiye
Nurşen Çakan Türkiye
Ali Akbaş Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | Clinical & Investigative Medicine (Q3) | ||
| Dergi ISSN | 0147-958X Dergi Bilgileri (2014) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2014 |
| Kabul Tarihi | – | Yayınlanma Tarihi | 01-08-2014 |
| Cilt / Sayı / Sayfa | 37 / 4 / 211–216 | DOI | 10.25011/cim.v37i4.21726 |
| Makale Linki | http://dx.doi.org/10.25011/cim.v37i4.21726 | ||
| UAK Araştırma Alanları |
Çocuk Sağlığı ve Hastalıkları (Çocuk Sağlığı ve Hastalıkları)
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| Özet |
| Purpose Vitamin D deficiency or insufficiency plays a role in the initiation and perpetuation of certain autoimmune diseases. The purpose of this study was to measure the vitamin D status of children with Familial Mediterranean Fever (FMF) and compare it to their healthy peers. Methods A total of 50 FMF patients and 49 healthy children were enrolled in this prospective study. Vitamin D levels were measured via HPLC. Demographic data, FMF symptom severity scores and the levels of other disease activity markers were retrieved from our hospital database. Results The mean age and gender balance of patients and controls were similar, being 8.4±3.8 years and 19 male patients, and 9.1±3.0 years and 25 male controls, respectively. The mean 25(-OH) vitamin D3 levels were 15.94±9.66 μg/L in FMF patients and 41.22±21.31 μg/L in controls. Vitamin D levels were normal in 12% of FMF patients, insufficient in 62% and deficient in 26%. No vitamin D deficiency was evident in any control subject; 30% had insufficient and 70% had normal vitamin D levels. Plasma vitamin D3 levels were similar in all patients despite varying FMF symptom severity scores. Conclusions Vitamin D deficiency is frequent in children with FMF but is not associated with disease severity score. |
| Anahtar Kelimeler |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Yöksis | 3 |