Does long term ischemia affect the oxidant status during fracture healing
Yazarlar (7)
Ercan Çetinus
Prof. Dr. Metin Kılınç Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Prof. Dr. Murat Üzel Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Prof. Dr. Fatma İnanç Tolun Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Ergül Belge Kurutaş
Dr. Öğr. Üyesi Erkal BİLGİÇ Gaziosmanpaşa Üniversitesi, Türkiye
Ahmet Karaoğuz
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY (Q4) | ||
| Dergi ISSN | 0936-8051 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 07-2005 |
| Cilt / Sayı / Sayfa | 125 / 6 / 376–380 | DOI | 10.1007/s00402-005-0825-3 |
| UAK Araştırma Alanları |
Ortopedi ve Travmatoloji
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| Özet |
| IntroductionThe influence of transient circulatory arrest on oxidant status during the healing of a tibial fracture was investigated in rats by the use of a hindlimb tourniquet technique.Materials and methodsOne of the most reliable indicators for cytological damage is lipid peroxidation, which can be demonstrated by malondialdehyde (MDA) levels. Fifty-eight Wistar rats were used in this study. To determine the basal MDA levels of bone, 10 rats not exposed to ischemia were killed by an overdose of ether. The remaining 48 rats were randomly divided into two groups (control and ischemia). The control and ischemia groups were then randomly divided into 4 groups of 6 rats each. In 48 rats, the left tibia was fractured and fixed intramedullarly. In the ischemic group, complete acute transient ischemia for 4.5 h was imposed after the fracture. In the control group, no other intervention except the fracture was done. Rats from … |
| Anahtar Kelimeler |
| fracture healing | ischemia | tibial fractures | oxidative stress | malondialdehyde |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 19 |
| Google Scholar | 38 |