In Vitro Antidiabetic, Antiinflammatory, Cytotoxic, Antioxidant and Antimicrobial Activities of Pomegranate (Punica granatum L.) Peel
Yazarlar (4)
Doç. Dr. Tuğba Demir Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Özlem AKPINAR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Haki Kara Cumhuriyet Üniversitesi, Türkiye
Prof. Dr. Hüseyin Güngör Cumhuriyet Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Akademik Gida | ||
| Dergi ISSN | 1304-7582 Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2019 |
| Cilt / Sayı / Sayfa | 17 / 1 / 61–71 | DOI | 10.24323/AKADEMIK-GIDA.544647 |
| Makale Linki | https://dergipark.org.tr/en/download/article-file/679625 | ||
| UAK Araştırma Alanları |
Mühendislik
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| Özet |
| In this study, antioxidant, antimicrobial, antidiabetic, antiinflammatory and cytotoxic properties of the pomegranate (Punica granatum L.) peel were investigated. The composition of the phenolic compounds of the pomegranate peel extract (33%, 78°C, 113 min) was determined and it was found to contain high amounts of punigalagin, caffeic acid and epicatechin. At the same time, the extract was found to have high antioxidant capacity. It showed antimicrobial activity against selected microorganisms (Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Aspergillus flavus and Aspergillus niger) and its highest microbial resistance was found to be against S. aureus (21 mm; 1.87 mg extract /mL). It inhibited α-amylase and α-glucosidase enzymes and showed the antidiabetic property. At the same time, the extract was able to inhibit xanthine oxidase and lipoxygenase enzymes that were responsible for the inflammation and its cytotoxic activity on breast and bone cancer cells were also observed. It was concluded that pomegranate peel extracts could be used in food and non-food applications due to its biological activities. |
| Anahtar Kelimeler |
| Antidiabetic | Antiinflammatory | Antimicrobial | Cytotoxic | Pomegranate peel |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 14 |
| Google Scholar | 10 |