Relationship between left ventricular diastolic dysfunction and six minute walk test in patients with systemic sclerosis        
Yazarlar (12)
Ali Akdogan
Hacettepe Üniversitesi, Türkiye
Ergun B. Kaya
Hacettepe Üniversitesi, Türkiye
Prof. Dr. Abdurahman ŞAHİN Hacettepe Üniversitesi, Türkiye
Sercan Okutucu
Hacettepe Üniversitesi, Türkiye
Edibe Yakut
Hacettepe Üniversitesi, Türkiye
Umut Kalyoncu
Hacettepe Üniversitesi, Türkiye
Hakan Aksoy
Hacettepe Üniversitesi, Türkiye
Omer Karadag
Hacettepe Üniversitesi, Türkiye
Meral Calguneri
Hacettepe Üniversitesi, Türkiye
Lale Tokgozoglu
Hacettepe Üniversitesi, Türkiye
Sedat Kiraz
Hacettepe Üniversitesi, Türkiye
Ihsan Ertenli
Hacettepe Üniversitesi, Türkiye
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale
Dergi Adı International Journal of Rheumatic Diseases
Dergi ISSN 1756-1841 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Dergi Grubu Q4
Makale Dili İngilizce
Basım Tarihi 10-2011
Cilt No 14
Sayı 4
Sayfalar 379 / 383
DOI Numarası 10.1111/j.1756-185X.2011.01672.x
Makale Linki http://doi.wiley.com/10.1111/j.1756-185X.2011.01672.x
Özet
Objective: The six minute walk test (6MWT) is used for the assessment of functional capacity in pulmonary and cardiovascular diseases. Left ventricular diastolic dysfunction (LVDD) is the most common cardiac abnormality in systemic sclerosis (SSc). The aim of this study was to define the effect of LVDD on 6MWT parameters in patients with SSc. Methods: We studied 45 (female:male 40:5) SSc patients. Patients with obvious conditions that can affect 6MWT distance (6MWD) were excluded. All subjects were evaluated by 6MWT. Additionally, 6MWD of the participants was calculated as the percentage of normal predicted values. LVDD was assessed by using echocardiographic findings and classified into three categories: impaired relaxation, pseudonormal or restrictive. Results: There were 12 (27%) patients with LVDD. SSc patients with LVDD were older than SSc patients without LVDD (50±12years vs. 41±10years; P=0.017). In all, the mean 6MWD was 487.9±98.3m. The 6MWD was shorter in SSc patients with LVDD as compared to those without LVDD (438.0±94.7m vs. 506.0±94.5m; P=0.039). There was significant difference between the groups regarding the percentage of the predicted 6MWD (74.1±10.1%vs. 82.8±13.1%; P=0.041). Conclusion: The presence of LVDD alters 6MWD in SSc patients. Reduction of 6MWD in a patient with SSc should prompt the investigation of LVDD. © 2011 The Authors. International Journal of Rheumatic Diseases © 2011 Asia Pacific League of Associations for Rheumatology and Blackwell Publishing Asia Pty Ltd.
Anahtar Kelimeler
Diastolic dysfunction | Six minute walk test | Systemic sclerosis