HPLC-based methods for the determination of levetiracetam in biological and pharmaceutical samples
Yazarlar (4)
Doç. Dr. Oğuz ÖZBEK Zonguldak Bülent Ecevit Üniversitesi, Türkiye
Dr. Öğr. Üyesi Çağlar BERKEL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ömer IŞILDAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Meliha Burcu GÜRDERE Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği, araştırma notu, bilirkişi raporu ve benzeri) (SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not, editöre mektup, tartışma, vaka takdimi ve özet türünden makale) | ||
| Dergi Adı | Journal of the Indian Chemical Society (Q4) | ||
| Dergi ISSN | 0019-4522 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2022 |
| Kabul Tarihi | 12-04-2026 | Yayınlanma Tarihi | 01-05-2022 |
| Cilt / Sayı / Sayfa | 99 / 5 / 100348–0 | DOI | 10.1016/j.jics.2022.100348 |
| Makale Linki | http://dx.doi.org/10.1016/j.jics.2022.100348 | ||
| Özet |
| Levetiracetam is one of the new generation anti–epileptic agents (also known as anticonvulsants or antiseizure drugs). Following its approval for marketing in 2000, levetiracetam has been widely used in the treatment of epilepsy due to its broad spectrum effects. One of the advantages of this antiseizure drug is its rapid and complete absorption after oral administration. It has also minimal drug–drug and food interactions, and shows more than 95% bioavailability. The determination of levetiracetam in various samples is carried out using several analytical methods including HPLC–based methods. HPLC–based methods are used for different pharmaceutical analyses and play an important role in drug monitoring during patient follow–ups. This review provides a summary of the HPLC–based methods used in the determination and quantification of levetiracetam in biological fluids and pharmaceutical preparations. |
| Anahtar Kelimeler |
| Analytical methods | Anticolvulsant | Anti–epileptic | Drug analysis | HPLC | Levetiracetam | Liquid chromatography |
Science Direct
HPLC-based methods for the determination of levetiracetam in biological and pharmaceutical samples
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Google Scholar | 7 |
| Scopus | 3 |