Characterization and Comparative Investigation of In Vitro Bioactivities for Lactuca anatolica Root Aqueous Extract and Their Green-Chemical Synthesized Nanoparticles; Molecular Docking Studies
Yazarlar (6)
Noor Nayel Ondokuz Mayis Üniversitesi, Türkiye
Sarmad Marah Ondokuz Mayis Üniversitesi, Türkiye
Prof. Dr. Tevfik Özen Ondokuz Mayis Üniversitesi, Türkiye
Doç. Dr. İlyas YILDIZ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Lütfi Behçet Bingöl Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (ESCI dergilerinde yayınlanan tam makale)
Dergi Adı Bionanoscience
Dergi ISSN 2191-1630 Dergi Bilgileri (2024)
Dergi Tarandığı Indeksler ESCI, EBSCO, Google Scholar, INSPEC
Makale Dili İngilizce Basım Tarihi 09-2024
Kabul Tarihi 29-02-2024 Yayınlanma Tarihi 25-05-2024
Cilt / Sayı / Sayfa 14 / 3 / 2854–2871 DOI 10.1007/s12668-024-01353-9
Makale Linki https://doi.org/10.1007/s12668-024-01353-9
UAK Araştırma Alanları
Organik Kimya
Özet
The current study synthesized silver nanoparticle (AgNP) biosynthesis and sustainable biochemical approaches, molecular docking studies using endemic and medicinal L. anatolica root aqueous extract. AgNPs were characterized in detail by TEM, XRD, and spectroscopic techniques such as FT-IR and UV–vis. The bioactivity of AgNPs was investigated with antioxidant, anti-inflammatory, photocatalytic, antibacterial, enzyme inhibition, and DNA protection tests. The AgNP formation was verified by UV–vis examination at 440 nm and the XRD, which showed a clearly defined crystalline organization. The TEM picture revealed uniformly distributed with a spherical shape and an average diameter of 17.5 nm. The synthesized AgNP exhibited PMRA (A0.5, 0.10 µg/mL), RPA (A0.5, 1.17 µg/mL), LPI (IC50, 1.10 µg/mL), DPPH• (IC50, 2.61 µg/mL), and ABTS•+ (IC50-6.21µg/mL) scavenging activities higher activity than the …
Anahtar Kelimeler
AgNP | Aqueous extract | Bioactivity | Lactuca anatolica L. root | Molecular docking