Phytochemical analysis and biological activity of Corchorus olitorius L.: Quantitative analysis of bioactive compounds by LC-MS/MS, antibacterial, enzyme inhibition, and cytotoxic activities
Yazarlar (9)
Mehmet Nuri Atalar Iğdır Üniversitesi, Türkiye
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Fikret Turkan Iğdır Üniversitesi, Türkiye
Mehmet Hakki Alma Iğdır Üniversitesi, Türkiye
Ibrahim Demirtas Iğdır Üniversitesi, Türkiye
Ayse Baran Mardin Artuklu University, Türkiye
Sevgi Irtegun Kandemir Dicle University, Faculty of Medicine, Türkiye
Ayse Ilgin Kekec Istanbul University-Cerrahpasa, Türkiye
Fatma Zerrin Saltan Anadolu Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı European Journal of Integrative Medicine (Q2)
Dergi ISSN 1876-3820 Dergi Bilgileri (2023)
Makale Dili İngilizce Basım Tarihi 09-2023
Kabul Tarihi – Yayınlanma Tarihi 01-09-2023
Cilt / Sayı / Sayfa 62 / 1 / 102290–0 DOI 10.1016/j.eujim.2023.102290
Makale Linki https://doi.org/10.1016/j.eujim.2023.102290
UAK Araştırma Alanları
Fen Bilimleri ve Matematik
Özet
IntroductionCorchorus olitorius L. is a significant plant in folk medicine, therefore, research on phytochemistry with biological activity may reveal its potential use in drug development. Medicinal plants are valuable sources of drug materials as they include bioactive compounds known as secondary metabolites. Determination of bioactive compounds and biological activity of plants lead to understanding their potential in drug development.MethodsA quantitative analysis of the bioactive compounds in leaf, stem, and root extracts of C. olitorius L. was carried out with Liquid Chromatography-Mass Spectrometry (LC–MS/MS). Acetylcholinesterase (AChE) and Glutathione-S-Transferase (GST) enzyme inhibition and  antibacterial effects were investigated using Mueller Hinton broth microdilution assay. The anticancer activity of C. olitorius leaves was evaluated by MTT assay using HDF, U87, Skov-3, and Caco-2 cell lines …
Anahtar Kelimeler
Antibacterial activity | Anticancer effect | Corchorus olitorius | Enzyme inhibition | Quantitative analysis