Chemical Composition, Antioxidant, Antimicrobial, Antidiabetic, and Butyrylcholinesterase Inhibitory Activities in Vitro of the Essential Oil and Crude Extracts of the Aerial Parts of Thymus ciliatus
Yazarlar (9)
Nadia Djermane Université Larbi Tébessi - Tébessa, Cezayir
Mostapha Brahmi Université Ahmed Zabana De Relizane, Cezayir
Djallal Eddine Adli Université Dr Taher Moulay Saida - Algeria, Cezayir
Micaela Gliozzi Università Degli Studi Magna Graecia Di Catanzaro, İtalya
Vincenzo Musolino Università Degli Studi Magna Graecia Di Catanzaro, İtalya
Rebbas Khellaf Université Ibn-Khaldoun Tiaret, Cezayir
Prof. Dr. Ramazan ERENLER Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Rabah Arhab Université Larbi Tébessi - Tébessa, Cezayir
Stefania Garzoli Sapienza Università Di Roma, İtalya
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Chemistry and Biodiversity (Q3)
Dergi ISSN 1612-1872 Dergi Bilgileri (2025)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 08-2025
Cilt / Sayı / Sayfa 22 / 8 / – DOI 10.1002/cbdv.202403318
Makale Linki https://doi.org/10.1002/cbdv.202403318
UAK Araştırma Alanları
Organik Kimya
Özet
This study explores the potential of Thymus ciliatus as a natural source of bioactive compounds by investigating its chemical composition and in vitro biological activities, including antioxidant, antimicrobial, antidiabetic, and anti‐Alzheimer properties. The analysis of the essential oil was performed using gas chromatography‐mass spectrometry revealing α‐terpinenyl acetate (18.74%) and camphor (10.62%) as the major components. Antioxidant activity was evaluated using six methods. Antimicrobial activity was assessed using disc diffusion and well diffusion techniques. Antidiabetic activity was measured through a colorimetric assay, while anti‐Alzheimer activity was evaluated against butyrylcholinesterase. The results demonstrated that extracts from polar and medium‐polar solvents exhibited the highest antioxidant activity, followed by low‐polar solvent extracts. The essential oil of T. ciliatus displayed significant …
Anahtar Kelimeler
antimicrobial activity | antioxidant activity | butyrylcholinesterase activity | GC-MS | α-glucosidase