Can risk groups accurately predict non‐sentinel lymph node metastasis in sentinel lymph node‐positive endometrial cancer patients? A Turkish Gynecologic Oncology Group Study (TRSGO‐SLN‐004)

Altın, Duygu; Taşkın, Salih; Çelik, Çetin; Köse, Mehmet Faruk; Ortaç, Uğur Fırat; Arvas, Mehmet Macit; Ayhan, Ali; Taşkıran, Çağatay; Tokgözoğlu, Nedim; Vatansever, Doğan; GÜLER, ABDÜL HAMİD; Güngör, Mete; Taşçı, Tolga; Turan, Hasan; Kahramanoğlu, İlker; Yalçın, İbrahim

doi:10.1002/jso.26310

Can risk groups accurately predict non‐sentinel lymph node metastasis in sentinel lymph node‐positive endometrial cancer patients? A Turkish Gynecologic Oncology Group Study (TRSGO‐SLN‐004)

Yazarlar (16)

Duygu Altın
Türkiye

Salih Taşkın
Ankara Üniversitesi, Türkiye

Nedim Tokgözoğlu

Doğan Vatansever Koç Üniversitesi, Türkiye

Dr. Öğr. Üyesi Abdül Hamid GÜLER Türkiye

Mete Güngör
Acıbadem Mehmet Ali Aydınlar Üniversitesi, Türkiye

Tolga Taşçı Türkiye

Hasan Turan
Türkiye

İlker Kahramanoğlu Biruni Üniversitesi, Türkiye

İbrahim Yalçın Ondokuz Mayıs Üniversitesi, Türkiye

Çetin Çelik Türkiye

Mehmet Faruk Köse Acıbadem Mehmet Ali Aydınlar Üniversitesi, Türkiye

Uğur Fırat Ortaç
Türkiye

Mehmet Macit Arvas
Türkiye

Ali Ayhan Başkent Üniversitesi, Türkiye

Çağatay Taşkıran
Koç Üniversitesi, Türkiye

Makale Türü	Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı	Journal of Surgical Oncology (Q4)
Dergi ISSN	0022-4790 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler	SCI-Expanded
Makale Dili	İngilizce	Basım Tarihi	02-2021
Cilt / Sayı / Sayfa	123 / 2 / 638–645	DOI	10.1002/jso.26310
Makale Linki	http://dx.doi.org/10.1002/jso.26310

Özet

AbstractBackground and ObjectivesThe purpose of this study was to find out the risk factors associated with non‐sentinel lymph node metastasis and determine the incidence of non‐sentinel lymph node metastasis according to risk groups in sentinel lymph node (SLN)‐positive endometrial cancer patients.MethodsPatients who underwent at least bilateral pelvic lymphadenectomy after SLN mapping were retrospectively analyzed. Patients were categorized into low, intermediate, high‐intermediate, and high‐risk groups defined by ESMO‐ESGO‐ESTRO.ResultsOut of 395 eligible patients, 42 patients had SLN metastasis and 16 (38.1%) of them also had non‐SLN metastasis. Size of SLN metastasis was the only factor associated with non‐SLN metastasis (p = .012) as 13/22 patients with macrometastasis, 2/10 with micrometastasis and 1/10 with isolated tumor cells (ITCs) had non‐SLN metastasis. Although all 4 metastases (1.8%) among the low‐risk group were limited to SLNs, the non‐SLN involvement rate in the high‐risk group was 42.9% and all of these were seen in patients with macrometastatic SLNs.ConclusionsNon‐SLN metastasis was more frequent in higher‐risk groups and the risk of non‐SLN metastasis increased with the size of SLN metastasis. Proceeding to complete lymphadenectomy when SLN is metastatic should further be studied as the effect of leaving metastatic non‐SLNs in‐situ is not known.

Anahtar Kelimeler

BM Sürdürülebilir Kalkınma Amaçları

Atıf Sayıları

Can risk groups accurately predict non‐sentinel lymph node metastasis in sentinel lymph node‐positive endometrial cancer patients? A Turkish Gynecologic Oncology Group Study (TRSGO‐SLN‐004)

Dergi Adı	JOURNAL OF SURGICAL ONCOLOGY
Yayıncı	Wiley-Liss Inc.
Açık Erişim	Hayır
ISSN	0022-4790
E-ISSN	1096-9098
CiteScore	4,2
SJR	0,741
SNIP	0,826

Can risk groups accurately predict non‐sentinel lymph node metastasis in sentinel lymph node‐positive endometrial cancer patients? A Turkish Gynecologic Oncology Group Study (TRSGO‐SLN‐004)

Paylaş