Comparison of the Relationship Between Inflammatory Markers and Atrial Fibrillation Burden
Yazarlar (3)
Dr. Öğr. Üyesi Sefa Erdi ÖMÜR
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Çağrı ZORLU
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
|
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | The Anatolian Journal of Cardiology |
| Dergi ISSN | 2149-2263 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | İngilizce |
| Basım Tarihi | 08-2023 |
| Cilt No | 27 |
| Sayı | 8 |
| Sayfalar | 486 / 493 |
| DOI Numarası | 10.14744/AnatolJCardiol.2023.2927 |
| Makale Linki | http://dx.doi.org/10.14744/anatoljcardiol.2023.2927 |
| Özet |
| Background: Atrial fibrillation is a complex disease with irregular ventricular response and tachycardia as a result of irregular and rapid contraction of the atria, with poor cardiovascular outcomes unless treated. Various mechanisms are involved in its patho- physiology. .Inflammation has an important place among these mechanisms. Many car- diovascular events accompany inflammation. Understanding and correct evaluation of inflammation in current situations contribute to the diagnosis and severity of the disease. The aim of our study was to understand the role of inflammatory biomarkers in patients with atrial fibrillation and to evaluate the difference between whether the disease is par- oxysmal and persistent (atrial fibrillation burden). Methods: The study was done retrospectively, and a total of 752 patients who were admitted to the cardiology outpatient clinic were recruited. The normal sinus rhythm group of the study consisted of 140 patients, and the atrial fibrillation group consisted of 351 [permanent atrial fibrillation (n = 206) and paroxysmal atrial fibrillation (n = 145)] patients. Inflammation markers were evaluated by dividing the patients into 3 groups. Results: Higher permanent atrial fibrillation [209.71 (40.73-604.0)], paroxysmal atrial fibrillation [188.51 (53.95-617.46)], normal sinus rhythm [629.47 (104-4695)]; permanent atrial fibrillation [4.53 (0.27-17.94)], paroxysmal atrial fibrillation [3.09 (0.40-11.0)], normal sinus rhythm [2.34 (0.61-13.51)] (P < .05); and permanent atrial fibrillation [1569.54 (139- 6069)], paroxysmal atrial fibrillation [1035.09 (133-4013)], normal sinus rhythm [130.40 (26.42-680.39)] (P < .05) were detected in the systemic immune inflammation index, neutrophil–lymphocyte ratio, and platelet/lymphocyte ratio atrial fibrillation groups compared to normal sinus rhythm group. Correlation between C-reactive protein and systemic immune inflammation index (r = 0.679, r = 0.483 P < .05, respectively) was found in the permanent atrial fibrillation and paroxysmal atrial fibrillation groups. Conclusion: Systemic immune inflammation index, neutrophil–lymphocyte ratio, and platelet–lymphocyte ratio were found to be higher in permanent atrial fibrillation com- pared to paroxysmal atrial fibrillation and in the whole atrial fibrillation group compared to the normal sinus rhythm group. This indicates that inflammation is associated with AF burden and the SII index is successful in reflecting this. |
| Anahtar Kelimeler |
| Atrial fibrillation | systemic immune inflammation index | neutrophil–lympho- cyte ratio | platelet–lymphocyte ratio | C-reactive protein |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| TRDizin | 2 |