The effects of oxytocin on penile tissues in experimental priapism model in rats
Yazarlar (7)
Doç. Dr. Engin KÖLÜKÇÜ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Şahin Kılıç Türkiye
Prof. Dr. Bekir Süha PARLAKTAŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Fikret ERDEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Velid Unsal Mardin Artuklu Üniversitesi, Türkiye
Prof. Dr. Doğan ATILĞAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Nihat ULUOCAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | International Urology and Nephrology | ||
| Dergi ISSN | 0301-1623 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 02-2019 |
| Cilt / Sayı / Sayfa | 51 / 2 / 231–238 | DOI | 10.1007/s11255-018-2046-z |
| Makale Linki | http://link.springer.com/10.1007/s11255-018-2046-z | ||
| Özet |
| PurposeThis study aimed to demonstrate the effects of oxytocin on penile tissues in ischemia–reperfusion injury developed after priapism.MethodsForty Wistar Albino strain male rats were divided into four groups. The control group (n = 10) was not intervened. In Group 2, a rat model of priapism was constructed and maintained for 1 h. In Group 3, reperfusion was ensured for 30 min following priapism. Rats in Group 4 rats were given oxytocin 30 min before the induction of reperfusion following priapism. All rats were penectomized, and adequate amounts of blood sample were drawn. Inflammation, vasocongestion, desquamation, and edema in penile tissue were scored between 0 and 3 points (0: normal, 1: mild, 2: moderate, 3: severe) to evaluate the severity of tissue damage. The activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), and the levels of malondialdehyde (MDA), and nitric … |
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BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 7 |