Effect of Magnesium Levels on the Progression of Contrast-induced Nephropathy in NSTEMI Patients Undergoing PCI
Yazarlar (4)
Doç. Dr. Sefa Erdi ÖMÜR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gülşen GENÇ TAPAR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Çağrı ZORLU Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Kayıhan KARAMAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
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Özgün Makale
(Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
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| Dergi Adı | Interventional Cardiology Perspectives | ||
| Dergi ISSN | 3062-3227 | ||
| Dergi Tarandığı Indeksler | TR DİZİN | ||
| Makale Dili | İngilizce | Basım Tarihi | 11-2025 |
| Cilt / Sayı / Sayfa | 1 / 3 / 112–118 | DOI | – |
| Makale Linki | https://intcarper.com/pdf/4458d962-0fb2-48a3-a23a-e35265f70f9b/articles/intercardiopers.2025.2025-9-1/112-118.pdf | ||
| UAK Araştırma Alanları |
Kardiyoloji
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| Özet |
| Background: Contrast-induced nephropathy (CIN) is the most common cause of hospital-acquired acute renal failure. The increased use of contrast media in diagnostic and interventional cardiac catheterization procedures and the increased frequency of these procedures have made CIN a common problem in clinical cardiology practice.Aim: The aim of our study was to understand the role of magnesium (Mg²+) levels in patients who developed CIN after non-ST elevation myocardial infarction (NSTEMI).Study Design: The study was conducted retrospectively and a total of 4,324 patients who applied to the cardiology clinic with NSTEMI were included in the study. Methods: This retrospective single-center study included 4,003 NSTEMI patients undergoing percutaneous coronary intervention (PCI). Patients with systemic inflammatory or rheumatologic diseases, hematologic disorders, renal or hepatic failure, infection, malignancy, or prior thrombolytic therapy were excluded. CIN was defined as an increase in serum creatinine≥ 25% or≥ 0.5 mg/dL within 48-72 hours after contrast exposure. Statistical analyses were performed using SPSS 26.0. Logistic regression identified independent predictors, and receiver operating characteristic (ROC) analysis determined the optimal magnesium cut-off for CIN prediction.Results: CIN occurred in 1,062 patients (26.5%). Patients who developed CIN were older and had higher rates of diabetes mellitus, lower systolic blood pressure, and lower left ventricular ejection fraction. Serum magnesium levels were significantly lower in patients with CIN. ROC analysis identified an Mg²+ cut-off of 2.13 mg/dL [area under … |
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