Antithrombotic Therapy Does Not Jeopardize Emergency Percutaneous Nephrostomy
  
Yazarlar (6)
Şahin Kılıç Sağlık Bilimleri Üniversitesi, Türkiye
Ahmet Şükrü Alparslan
T.C. Sağlık Bakanlığı, Türkiye
Doç. Dr. Engin KÖLÜKÇÜ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Çağatay Özsoy Aydın Adnan Menderes Üniversitesi, Türkiye
Murat Şambel
Sağlık Bilimleri Üniversitesi, Türkiye
Selim Taş Sağlık Bilimleri Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (Ulusal alan endekslerinde (TR Dizin, ULAKBİM) yayınlanan tam makale)
Dergi Adı The new journal of urology
Dergi ISSN 3023-6940
Dergi Tarandığı Indeksler TR DİZİN
Makale Dili İngilizce Basım Tarihi 03-2025
Cilt / Sayı / Sayfa 20 / 1 / 13–20 DOI 10.33719/nju1603500
Makale Linki https://dergipark.org.tr/en/download/article-file/4449614
Özet
Objective: This study aims to evaluate the outcomes of patients on antithrombotic (antiaggregant and anticoagulant) therapy who underwent emergency percutaneous nephrostomy (PN) for complicated upper urinary tract infection. Materials and Methods: Data from consecutive patients who underwent emergency PN from January 2014 to October 2024 were retrospectively reviewed. A total of 34 patients on antithrombotic treatment (Group 1) and 35 control group patients (Group 2) without bleeding disorders or antithrombotic treatment were included. Demographics, PN indications, pre- and post-procedural haematological, biochemical, and microbiological parameters and complications were analysed. Results: The mean age was 67.82±9.73 in group 1 and 63.06±11.58 in group 2 (p=0.006). Sex distribution and indications for PN were comparable between groups. There was no significant difference in emergency PN indications, hydronephrosis grades, and PN placement sides. The most common antithrombotic in group 1 was warfarin (44.1 %). Escherichia coli was the most frequently isolated bacteria in both groups (55.9% vs. 48.6 % for groups 1 and 2, respectively). No major complication was observed in both groups after PN procedure. Blood replacement was performed in 4 and 3 patients in groups 1 and 2, respectively. Post-procedure mean Hg levels were similar in both groups (9.53 ±1.39 vs. 9.98 ±1.18 for groups 1 and 2, respectively). No difference in median hospital stay was observed between the groups. Conclusion: Antithrombotic drugs pose potential bleeding risks during PN placement. This is the first study in the literature on PN placement in patients on antithrombotic therapy and it indicates that the procedure can be performed with low complication rates in patients on antithrombotic therapy.
Anahtar Kelimeler
Percutaneous nephrostomy | Anticoagulant | Antiaggregant | Emphysematous pyelonephritis | Pyelonephrosis | Urological emergency.
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Atıf Sayıları
Antithrombotic Therapy Does Not Jeopardize Emergency Percutaneous Nephrostomy

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