Utility of TyG-Based Indices for Predicting Insulin Resistance in Turkish Adults: Insights from the TEKHAP Study
Yazarlar (5)
Prof. Dr. Ayşe Kevser Demir Türkiye
Doç. Dr. Şafak ŞAHİN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Rıza ÇITIL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Osman DEMİR Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Doç. Dr. Zeliha Cansel ÖZMEN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
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| Dergi Adı | JOURNAL OF CLINICAL MEDICINE (Q1) | ||
| Dergi ISSN | 2077-0383 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | İngilizce | Basım Tarihi | 12-2025 |
| Cilt / Sayı / Sayfa | 14 / 24 / 8965–0 | DOI | 10.3390/jcm14248965 |
| Makale Linki | https://doi.org/10.3390/jcm14248965 | ||
| UAK Araştırma Alanları |
Halk Sağlığı
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| Özet |
| Background/Objectives Insulin resistance (IR) is a key feature of metabolic disorders and a major precursor of type 2 diabetes and cardiovascular disease. The triglyceride–glucose (TyG) index and TyG-based indices—including TyG–body mass index (TyG–BMI), TyG–waist circumference (TyG–WC), and TyG–waist-to-height ratio (TyG–WHtR), have been proposed as simple, cost-effective surrogate markers of IR. However, population-based data from Türkiye are limited. To evaluate the association between TyG-based indices, triglycerides/high-density lipoprotein cholesterol (TG/HDL-C) ratio, and IR defined by Homeostasis Model Assessment–IR (HOMA-IR) in adults from the TEKHAP study—a province-wide, population-based survey in Tokat, Türkiye. Methods A total of 1854 adults (≥20 years) were included in the analysis. Physiologically implausible HOMA-IR outliers were identified using statistical criteria and … |
| Anahtar Kelimeler |
| insulin resistance | triglyceride-glucose index | TyG-based indices | HOMA-IR | TG/HDL-C ratio | surrogate biomarker |
BM Sürdürülebilir Kalkınma Amaçları
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| Google Scholar | 1 |