Chemical Characterization f The Fatty Acid Compositions And Antimicrobial Activity of Sumac (Rhus coriaria L.) Fruits, Growing Naturally in Turkey And Sold in Herbalist Markets
Yazarlar (4)
Doç. Dr. Gülderen YILMAZ Ankara Üniversitesi, Türkiye
Doç. Dr. Gülnur Ekşi Bona Ankara Üniversitesi, Türkiye
Prof. Dr. Betül Demirci Anadolu Üniversitesi, Türkiye
Prof. Dr. Fatih Demirci Anadolu Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SCOPUS dergilerinde yayınlanan tam makale)
Dergi Adı Ankara Universitesi Eczacilik Fakultesi Dergisi
Dergi ISSN 2564-6524 Scopus Dergi
Dergi Tarandığı Indeksler Scopus
Makale Dili İngilizce Basım Tarihi 01-2020
Cilt / Sayı / Sayfa 44 / 1 / 61–69 DOI 10.33483/jfpau.645467
Makale Linki https://dergipark.org.tr/tr/doi/10.33483/jfpau.645467
UAK Araştırma Alanları
Farmasotik Botanik
Özet
Objective: The aim of this study was to compare the fatty acid components and antimicrobial properties of R. coriaria L. samples which were sold as powder and grains that show natural distribution in Tunceli and Siirt. Material and Method: After the seeds were weighed and powdered, fixed oils were obtained by using soxhalet apparatus. Obtained fixed oils were analyzed by GC and GC / MS methods after methylation process. In vitro antimicrobial activity studies of the samples were performed using six different Gram negative and Gram positive bacteria and Candida albicans using EUCAST disc diffusion and CLSI microdilution methods. Result and Discussion: The main fatty acid components of all samples were determined as oleic acid (42.2 - 43.3%), linoleic acid (25.2 - 28.5%) and palmitic acid (18.4-221.5%), respectively. In vitro antimicrobial activity of fixed oils, such as Escherichia coli NRRL B-3008, Staphylococcus aureus ATCC 6538, S. epidermidis ATCC 14990, Pseudomonas aeruginosa ATCC 27853, Bacillus subtilis NRRL B-A78 A78. Results were compared with standard antimicrobial agents and MIC values> 2.5 - 0.22 mg/ml. The results were found to be significant in terms of antimicrobial efficacy.
Anahtar Kelimeler
Antimicrobial | CLSI | EUCAST | GC-FID | GC-MS | Rhus coriaria