Phytochemical analysis, antioxidant, and enzyme inhibition activity of five Salvia taxa from Turkey
Yazarlar (7)
Doç. Dr. Gülderen YILMAZ Ankara Üniversitesi, Türkiye
Prof. Dr. Nuraniye Eruygur Selçuk Üniversitesi, Türkiye
Doç. Dr. Gülnur Ekşi Bona İstanbul Medipol Üniversitesi, Türkiye
Prof. Dr. Mehmet Bona Istanbul Üniversitesi, Türkiye
Arş. Gör. Mehmet Akdeniz Dicle Üniversitesi, Türkiye
Doç. Dr. Mustafa Abdullah Yılmaz Dicle Üniversitesi, Türkiye
Prof. Dr. Abdulselam Ertaş Dicle Üniversitesi, Türkiye
Makale Türü Açık Erişim Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı South African Journal of Botany (Q2)
Dergi ISSN 0254-6299 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 01-2023
Cilt / Sayı / Sayfa 152 / 1 / 212–221 DOI 10.1016/j.sajb.2022.11.027
Makale Linki http://dx.doi.org/10.1016/j.sajb.2022.11.027
UAK Araştırma Alanları
Farmasotik Botanik
Özet
Salvia L. species are widely used for treatment of different disorders in traditional Turkish medicine. In this study, the methanol extracts of five Salvia taxa, including S. aucheri subsp. canescens, S. aytachii, S. heldreichiana, S. viridis, and S. wiedemannii were investigated for their antioxidant activity and enzyme inhibitory potentials which are related with health-benefit properties. In addition, total phenolic and flavonoid contents were determined with Folin- Ciocalteu and aluminum chloride spectrophotometric method, respectively. Screening of enzyme inhibition activity was performed out using ELISA microplate reader. Antioxidant activity was evaluated by 2,2′-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′ -Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging and iron chelating tests. The S. aytachii extract was found with highest total phenol content (77.82 ± 1.76 µg PE/mg) and total flavonoid content (22.33 ± 0.17 µg QE/mg) as dry weight basis. These findings specify that the investigated Salvia taxa for anticholinesterase activity can be appealed further phytochemical estimation for spotting its active components.
Anahtar Kelimeler
Antioxidant | Enzyme inhibition | LC-MS/MS | Phytochemical | Salvia