EVALUATION OF FATTY ACID COMPOSITIONS AND ANTIMICROBIAL EFFECTS OF CELTIS AUSTRALIS L. AND C. TOURNEFORTII LAM. (CANNABACEAE) NATURALLY DISTRIBUTED IN TURKEY
Yazarlar (3)
Doç. Dr. Gülderen YILMAZ Ankara Üniversitesi, Türkiye
Dr. Öğr. Üyesi Gözde Öztürk Anadolu Üniversitesi, Türkiye
Prof. Dr. Betül Demirci Anadolu Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(SCOPUS dergilerinde yayınlanan tam makale)
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| Dergi Adı | Ankara Universitesi Eczacilik Fakultesi Dergisi | ||
| Dergi ISSN | 2564-6524 Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 01-2021 |
| Cilt / Sayı / Sayfa | 45 / 3 / 480–490 | DOI | 10.33483/jfpau.863486 |
| UAK Araştırma Alanları |
Farmasotik Botanik
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| Özet |
| Objective: The aim of this study was to compare the fatty acid components and antimicrobial properties of fruit samples of Celtis australis L. ve C. tournefortii Lam. naturally grown in Turkey. Material and Method: The fixed oils were obtained from the fruits of C. australis and C. tournefortii by using Soxhlet apparatus, and then methylated. The components of the obtained fatty acids were analyzed simultaneously by GC and GC/MS. The in vitro antimicrobial activity of the fatty acid samples were determined against Gram negative Pseudomonas aeruginosa ATCC 27853, Salmonella typhimurium ATCC 13311 and Gram positive Staphylococcus aureus ATCC 6538, Bacillus cereus NRRL B3711, Propionibacterium acnes ATCC 11827, Streptococcus mutans ATCC 25175 Staphylococcus aureus ATCC 700699 microorganisms using the CLSI microdilution method. Chloramphenicol was used as positive control. The minimum inhibition concentrations (mg/mL) were designated. Result and Discussion: The unsaturated fatty acid in C. australis and C. tournefortii fruits were determined as linoleic acid (74,8%, 49,5%), oleic acid (10,8%, 18,6%) and palmitic acid (5,6%, 8,8%), respectively. Results were compared with standard antimicrobial agents and MIC values > 2,5-0,5mg mg / mL were determined. The results were found to be significant in terms of antimicrobial efficacy. |
| Anahtar Kelimeler |
| Antimicrobial | Celtis australis | Celtis tournefortii | Fatty acid | GC-MS |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 1 |