The biochemical effects of ischemia-reperfusion injury in the ipsilateral and contralateral testes of rats and the protective role of melatonin
Yazarlar (7)
Bekir S. Parlaktas
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Doğan ATILĞAN Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Huseyin Ozyurt
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Yusuf Gencten
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Ali Akbas Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Fikret Erdemir Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Nihat Uluocak Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü |
Özgün Makale
(ESCI dergilerinde yayınlanan tam makale)
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| Dergi Adı | Asian Journal of Andrology | ||
| Dergi ISSN | 1008-682X Wos Dergi Scopus Dergi | ||
| Makale Dili | İngilizce | Basım Tarihi | 03-2014 |
| Cilt / Sayı / Sayfa | 16 / 2 / 314–318 | DOI | 10.4103/1008-682X.122202 |
| Makale Linki | https://journals.lww.com/ajandrology/fulltext/2014/16020/the_biochemical_effects_of_ischemia_reperfusion.25.aspx | ||
| UAK Araştırma Alanları |
Üroloji
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| Özet |
| Testicular torsion (TT) is a serious urologic emergency that is observed in adolescent males and that can lead to infertility if left untreated. The ischemia-reperfusion (I/R) injury due to TT has been implicated in the pathogenesis of testicular damage. We investigated the effects of melatonin on oxidative damage in the ipsilateral and contralateral testes of rats induced by unilateral TT. A total of 21 prepubertal male Wistar albino rats were divided into three groups, each consisting of seven rats. In Group 1 (SHAM group): a sham operation to the left testis and bilateral orchiectomy were performed. In Group 2 (I/R group): I/R injury was created by rotating the left testis 720 in a clockwise direction for 2 h and detorsing the testis after 2 h. Group 3 (I/R+ MEL group): rats were subjected to I/R injury and one-shot melatonin injection (50 mg kg− 1, intraperitoneal (ip)). The testes of the rats were excised bilaterally in all groups. The … |
| Anahtar Kelimeler |
| Antioxidant enzymes | Ischemia-reperfusion (I/R) | Lipid peroxidation | Melatonin | Testicular torsion (TT) |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 57 |
| Scopus | 63 |
| Google Scholar | 90 |