The effects of circulating MIR22-3p and MIR16-1-3p levels in different stages of subacute thyroiditis
Yazarlar (6)
Doç. Dr. Nevin KARAKUŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Dr. Öğr. Üyesi Merve ÇATAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Faruk Kutlutürk
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Mustafa Koçak Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Merve Akman Ekici
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Muhterem Çıtır
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Nucleosides Nucleotides and Nucleic Acids (Q4) | ||
| Dergi ISSN | 1525-7770 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 02-2023 |
| Cilt / Sayı / Sayfa | 42 / 6 / 436–447 | DOI | 10.1080/15257770.2022.2154360 |
| Makale Linki | http://dx.doi.org/10.1080/15257770.2022.2154360 | ||
| UAK Araştırma Alanları |
Tıbbi Biyoloji
|
||
| Özet |
| Subacute thyroiditis (SAT) is an inflammatory thyroid disease with a frequency is 5% among all thyroid diseases. miRNAs are endogenous, non-coding RNAs ranging in length from 19 to 25 nucleotides. They play an important role in the posttranscriptional regulation of gene expression. In this study, we aimed to investigate whether the expression levels of two circulating miRNAs, MIR22 and MIR16-1, can be used as a parameter in the diagnosis and follow-up of SAT disease. Fifty patients diagnosed with SAT and 41 healthy controls were included in this study. Expression levels of miRNAs were determined by real time-PCR method. Expression data of miRNAs were calculated by fold change (2-ΔΔCt) method. The statistical significance of miRNA expression was evaluated by t-test. The expression levels of MIR22-3p and MIR16-1-3p were not found to be statistically different between SAT patients and controls and … |
| Anahtar Kelimeler |
| expression level | MIR16-1 | MIR22 | Subacute thyroiditis |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 1 |
| Google Scholar | 1 |