Keggin POM-based hybrids decorated with aminopyridines. Determination of their molecular structure, electrochemical behaviors, antimicrobial and anticancer activities
Yazarlar (6)
Eyup Akgün
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Prof. Dr. Nihal DELİGÖNÜL Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Arş. Gör. Büşra Albayrak Mısır Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Prof. Dr. Mehmet Tümer Kahramanmaraş Sütçü İmam Üniversitesi, Türkiye
Doç. Dr. Sabahattin Cömertpay Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
Prof. Dr. Muhammet Köse Kahramanmaras Sütçü Imam Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Journal of Molecular Structure (Q2) | ||
| Dergi ISSN | 0022-2860 Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 07-2025 |
| Cilt / Sayı / Sayfa | 1347 / 1 / 143278–0 | DOI | 10.1016/j.molstruc.2025.143278 |
| Makale Linki | https://doi.org/10.1016/j.molstruc.2025.143278 | ||
| UAK Araştırma Alanları |
Anorganik Kimya
Biyokimya
Fotokimya
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| Özet |
| Two novel Keggin-type polyoxometalate (POM)-based organic–inorganic hybrid compounds, K-ABP and K-ACP, were synthesized by reacting the Keggin POM anion with 3-amino-5-bromopyridine (ABP) and 2-amino-5-chloropyridine (ACP), respectively. Single-crystal X-ray diffraction revealed that both compounds crystallize in the triclinic P‒1 space group, featuring classical Keggin structures stabilized by organic ligands. Spectroscopic techniques confirmed the structural integrity of the hybrids, highlighting characteristic POM vibrations and charge-transfer transitions. Electrochemical analysis showed multiple redox processes, with K-ACP exhibiting more complex behavior due to structural variations. Biological assays indicated minor groove DNA binding for both hybrids, with stronger affinity observed for K-ACP. K-ABP, in particular, exhibited pronounced DNA cleavage activity, suggesting genotoxic potential … |
| Anahtar Kelimeler |
| Anticancer | Antimicrobial | Crystal structure | DNA binding and cleavage | Hybrids |
Science Direct
Keggin POM-based hybrids decorated with aminopyridines. Determination of their molecular structure, electrochemical behaviors, antimicrobial and anticancer activities
| Atıf Sayıları | |
| Web of Science | 2 |
| Scopus | 2 |
| Google Scholar | 2 |