Bioactivity, free radical scavenging properties, hCA I and hCA II esterase activities of tetraamino-(9-ethyl-3-carbazolyl)-(NN)-spirocyclotriphosphazenes: Synthesis, characterization, and structure–activity relationship (SAR) studies
Yazarlar (10)
Prof. Dr. Hüseyin AKBAŞ Tokat Gaziosmanpaşa Üniversitesi, Türkiye
Prof. Dr. Aytuğ Okumuş Ankara Üniversitesi, Türkiye
Öğr. Gör. Zeynel Kılıç Ankara Üniversitesi, Türkiye
Tuncer Hökelek
Hacettepe Üniversitesi, Türkiye
Hacettepe Üniversitesi, Türkiye
Büşra Nur Sabah Gazi Üniversitesi, Türkiye
Prof. Dr. Leyla Açık Gazi Üniversitesi, Türkiye
Süheyla Pınar Çelik Gazi Üniversitesi, Türkiye
Ekrem Tunca Dumlupinar Üniversitesi, Türkiye
Nagihan Kaya Dumlupinar Üniversitesi, Türkiye
Doç. Dr. Ayşegül ŞENOCAK Tokat Gaziosmanpaşa Üniversitesi, Türkiye
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | Chemical Papers (Q3) | ||
| Dergi ISSN | 0366-6352 Dergi Bilgileri (2025) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 08-2025 |
| Cilt / Sayı / Sayfa | 79 / 10 / 7211–7233 | DOI | 10.1007/s11696-025-04259-2 |
| Makale Linki | https://link.springer.com/article/10.1007/s11696-025-04259-2#citeas | ||
| UAK Araştırma Alanları |
Anorganik Kimya
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| Özet |
| In this study, hexachlorocyclotriphosphazene (HCCP) was reacted with diamines (9-ethyl-N-methyl-3-carbazolyl-1,2-diaminoethane, 9-ethyl-N-ethyl-3-carbazolyl-1,2-diaminoethane, and 9-ethyl-N-methyl-3-carbazolyl-1,3-diaminopropane) to synthesize the precursor compounds tetrachloro-(9-ethyl-3-carbazolyl)-(NN)-spiro-cyclotriphosphazenes, (N3P3)[(CzSpiro-n)R]Cl4. In these compounds, Cz refers to 9-ethyl carbazolyl, R represents the substituent group (Me or Et), and n denotes the chain length {n = 5 for R = –CH3 (1), n = 5 for R = –CH2CH3 (2), and n = 6 for R = –CH3 (3)}. Tetraamino-(9-ethyl-3-carbazolyl)-(NN)-spirocyclotriphosphazenes (1a-3a, 1b-3b, 1c-3c, and 1d-3d) were prepared by the replecament reactions of compounds 1–3 with pyrrolidine, piperidine, morpholine, and 1,4-dioxa-8-azaspiro[4,5]decane (DASD), respectively. The structures of carbazolyl-(NN)-spirocyclotriphosphazenes … |
| Anahtar Kelimeler |
| Antioxidant | Bioactivity | hCA I and hCA II activity | Spirocyclotriphosphazene | Synthesis |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Scopus | 2 |
| Google Scholar | 3 |